different ossificant materials have been used for induction of bone repair in many studies, and bone matrix gelatin which contains bone morphogenic proteins is one of the best ones. in present study we evaluated the role of this material in acceleration of bone repair in rabbit tibia. a hole of 3.5 mm diameter was made on right tibia of 10 and 12 rabbits as study and control group respectively....

Primary cartilaginous lesions of the larynx are relatively uncommon. We present a case of bilaterally pseudocystic lesion of the thyroid cartilage that demonstrated progressive calcification. Pathologic analysis showed features suggesting a dystrophic lesion with no evidence of malignancy. We hypothesize that repetitive microtrauma related to muscular overuse probably led to inflammatory change...

PURPOSE To determine whether very radiodense material within a sinonasal soft-tissue mass on CT can be differentiated as calcification, ossification, or residual bone. METHODS We retrospectively described the radiodensities within 235 sinonasal soft-tissue masses as discrete, solitary or multiple, or as a diffuse process with either a well-defined or poorly defined margin. They were also clas...

BACKGROUND Primary osteosarcoma of the breast is an extremely rare lesion. The pathogenesis of primary osteosarcomas is controversial. CASE PRESENTATION We present the case of a 63-year-old white German woman who presented with a mass in her right breast after routine screening. The core needle biopsy showed ductal hyperplasia with metaplastic ossification of the breast tissue. Complete excis...

L ipomas are the most common benign soft-tissue tumors occurring in the subcutis or muscular regions. Histologically, lipoma consists of mature adipose cells, similar to normal adipose cells. Lipomas can occasionally have areas of bone or cartilage formation and are classified as osteolipomas or chondrolipomas, respectively. However, there have been few reported cases of lipoma with both ossifi...

Inflammatory myofibroblastic tumor is an uncommon benign neoplasm and its presentation in small bowel is rare. Due to clinical manifestation, laboratory data and radiologic results, there is an increased risk of over diagnosis as malignant tumors particularly malignant lymphoma in childhood therefore may be resulting in wrong therapeutic approach. However pathologic findings could be demonstrat...

A cardiac myxoma, a rare but relatively common tumor, was surgically excised. Histopathological examination of the lesion revealed an extensive internal ossification. Ossification interior myxomas is rarely reported, and most are large tumors; however, this case small tumor. The cause ossification has not yet been clearly reported.

Understanding the development of a skull deformity requires an understanding of the normal morphogenesis of the cranium. Craniosynostosis is the premature, pathologic ossification of one or more cranial sutures leading to skull deformities. A review of the English medical literature using textbooks and standard search engines was performed to gather information about the prenatal development an...

Calcification of the auricular cartilages is a very rare finding observed in metabolic disorders like Addison's disease, adrenal insufficiency or diabetes. Its aetiology and physiopathological mechanisms remain unclear. It may be caused by exposure to cold or trauma in the cartilage but in a significant number of cases, ossification occurs without the identification of the precipitating cause o...

PURPOSE Lung volume reduction surgery (LVRS) has re-emerged as an alternative in the management of patients with chronic, debilitating, emphysematous lung disease. This has permitted the formal evaluation of pathologic pulmonary changes present in these patients. This study seeks to describe systematically the pathologic findings present in patients undergoing LVRS. METHODS Tissue sections st...