BACKGROUND Recent studies have suggested that the presence of a pathological fracture does not impact on oncologic outcomes and the feasibility of limb salvage surgery (LSS) in appropriately selected patients when combined with neoadjuvant chemotherapy. These have largely been single institutional studies with limited numbers. The Eastern Asian Musculoskeletal Oncology Group reviewed the data f...

PURPOSE Women with breast cancer are at increased risk for femur fracture. Contributing factors include estrogen deficiency, cancer-related therapies, or direct bone involvement. This study examines fracture subtypes in women with prior breast cancer experiencing a femur fracture. METHODS Women age ≥50 years old with a history of invasive breast cancer who experienced a femur fracture were id...

OBJECTIVE To review our experience with late Marx stage III osteoradionecrosis (ORN) of the mandible in patients who present with pathologic fracture. STUDY DESIGN Case series with chart review. SETTING Tertiary care center. SUBJECTS AND METHODS Thirty-seven patients were identified from June 1998 to August 2010 who underwent treatment of Marx grade III osteoradionecrosis with pathologic ...

PURPOSE To review records of 8 patients with telangiectatic osteosarcoma (TOS) and determine whether pathologic fractures correlate with recurrence and survival. METHODS Records of 4 men and 4 women aged 17 to 44 (mean, 28) years treated for TOS were reviewed. RESULTS; Of the 8 patients, 4 developed a pathologic fracture and 4 did not. In each group, 2 patients underwent limb salvage surgery ...

The earliest efforts to predict the risk of an impending fracture in the presence of tumor dates to the 1960s [1–3, 10, 11]. Although some of the earlier studies made positive contributions, they lacked supportive statistical evidence. Later, several larger and well-documented studies were designed to identify the features of an impending pathologic fracture [4, 7, 8]. Although the statistical ...

Fractures in the jaw bones could present themselves differently according to the strength of the force and the bone's ability to absorb the impact. The location and type of the fracture is important as well as the cause of the fracture (traffic accidents, melee trauma, pathologic changes). Pre-existing pathologic lesions, position of the teeth and the way they are affected by the fracture have ...

Solitary plasmacytoma of bone is a rare malignant tumor mostly involving the axial skeleton. The tumor occurs in middle- aged or elderly people (mean age: 55 years) and has a high risk of progression to multiple myeloma. Radiotherapy is the preferred treatment for this disease. We report a case of recurrent solitary plasmacytoma of the fourth lumbar vertebra in a 35-year-old male. The patient s...