Wolfram Syndrome (WFS) is a rare autosomal recessive disease characterized by insulin-dependent diabetes mellitus, optic nerve atrophy, diabetes insipidus, deafness, and neurological dysfunction leading to death in mid-adulthood. WFS is caused by mutations in the WFS1 gene, which lead to endoplasmic reticulum (ER) stress-mediated cell death. Case studies have found widespread brain atrophy in l...

Wind farms (WFs) can affect the local climate, and local climate change may influence underlying vegetation. Some studies have shown that WFs affect certain aspects of the regional climate, such as temperature and rainfall. However, there is still no evidence to demonstrate whether WFs can affect local vegetation growth, a significant part of the overall assessment of WF effects. In this resear...

We introduce a scheme for constructing partly occupied, maximally localized Wannier functions (WFs) for both molecular and periodic systems. Compared to the traditional occupied WFs the partly occupied WFs possess improved symmetry and localization properties achieved through a bonding-antibonding closing procedure. We demonstrate the equivalence between bonding-antibonding closure and the mini...

Wolfram syndrome (WFS), caused by recessive mutations inWFS1, is characterized by neurodegeneration due to apoptosis provoked by increased endothelial reticulum stress (1). Currently, it is incurable and leads to a premature death at an average age of 35 years (2). Despite initial success with spectroscopybased studies (3), there is a lack of repeatable and robust markers for monitoring the cli...

In the first phase of each of two experiments, participants learned to associate a set of labels (i.e., consonant-vowel-consonant [CVC]) with a set of line lengths by using a paired-associate learning procedure. In the second phase of each experiment, these learned labels were used as memorial standards in the method of constant stimuli. Psychometric functions and the associated indices of disc...

BACKGROUND Classically characterized by early onset insulin-dependent diabetes mellitus, optic atrophy, deafness, diabetes insipidus, and neurological abnormalities, Wolfram syndrome (WFS) is also associated with atypical brainstem and cerebellar findings in the first decade of life. As such, we hypothesized that gait differences between individuals with WFS and typically developing (TD) indivi...

We present a new and general approach of deening semantics for disjunc-tive logic programs. Our framework consists of two parts: (1) a semantical, where semantics are deened in an abstract way as the weakest semantics satisfying certain properties, and (2) a procedural, namely a bottom-up query-evaluation method based on operators working on conditional facts (introduced independently by Bry an...

The purpose of the WFS specification, proposed by the the OpenGIS Consortium (OGC), is to describe the manipulation operations over geospatial data using GML. Web servers providing WFS service are called WFS Servers. WFS servers publish GML views of geographic features stored in data sources such that the user can query and update data sources through a user defined feature type schema. In this...

Abstract The algorithm wingsuit flying search (WFS) mimics the procedure of landing vehicle. outstanding feature WFS is parameterless and rapid convergence. However, also has its shortcomings, sometimes it will inevitably be trapped into local optima, thereby yield inferior solutions owing to relatively weak exploration ability. Spherical evolution (SE) adopts a novel spherical pattern that tak...

A novel systematic framework of medical image analysis, weighted Fourier series (WFS) analysis is introduced. WFS is a combination of Fourier series and heat kernel smoothing. WFS effectively reduces the Gibbs phenomenon, improves the signal to noise ratio, and increases normality of the estimated errors in the WFS-based generalized linear models. In estimating the parameters of WFS, the least ...