We have recently demonstrated that sensitive and chemically specific NMR spectra can be recorded in the absence of a magnetic field using hydrogenative parahydrogen induced polarization (PHIP) (1-3) and detection with an optical atomic magnetometer. Here, we show that non-hydrogenative parahydrogen-induced polarization (4-6) (NH-PHIP) can also dramatically enhance the sensitivity of zero-fiel...

The n3 and n4 vibrational transitions of methane trapped in solid parahydrogen have been observed by using Fourier transform infrared and high resolution laser spectroscopy. The observed spectrum is interpreted in terms of rovibrational states of the spherical rotor which are subjected to the crystal field splitting. The n4 band shows extremely sharp lines of a width of ;0.003 cm , while the n3...

This paper contains new, representative equations for the thermal conductivity of normal and parahydrogen. The equations are based in part upon a body of experimental data that has been critically assessed for internal consistency and for agreement with theory whenever possible. Although there are sufficient data at normal temperatures, data at very low or very high temperatures as well as near...

Alkali atoms trapped in solid hydrogen matrices have demonstrated ultralong electron spin coherence times and are promising as quantum sensors. Their is limited by magnetic noise from naturally occurring orthohydrogen molecules the parahydrogen matrix. In gas phase, component of can be converted to flowing it over a catalyst held at cryogenic temperatures, with lower temperatures giving fractio...

Parahydrogen induced polarization using heterogeneous catalysis can produce impurity-free hyperpolarized gases and liquids, but the comparatively low signal enhancements and limited scope of substrates that can be polarized pose significant challenges to this approach. This study explores the surface processes affecting the disposition of the bilinear spin order derived from parahydrogen in the...

NMR signal amplification by reversible exchange (SABRE) is a NMR hyperpolarization technique that enables nuclear spin polarization enhancement of molecules via concurrent chemical exchange of a target substrate and parahydrogen (the source of spin order) on an iridium catalyst. Recently, we demonstrated that conducting SABRE in microtesla fields provided by a magnetic shield enables up to 10% ...

Long-lived spin states of hyperpolarized propane-d6 gas were demonstrated following pairwise addition of parahydrogen gas to propene-d6 using heterogeneous parahydrogen-induced polarization (HET-PHIP). Hyperpolarized molecules were synthesized using Rh/TiO2 solid catalyst with 1.6 nm Rh nanoparticles. Hyperpolarized (PH ∼ 1%) propane-d6 was detected at high magnetic field (9.4 T) spectroscopica...

Direct NMR hyperpolarization of naturally abundant (15)N sites in metronidazole is demonstrated using SABRE-SHEATH (Signal Amplification by Reversible Exchange in SHield Enables Alignment Transfer to Heteronuclei). In only a few tens of seconds, nuclear spin polarization P(15)N of up to ∼24% is achieved using parahydrogen with 80% para fraction corresponding to P(15)N ≈ 32% if ∼100% parahydroge...

Previous pressure broadening results for the normal hydrogen/water system displayed a dramatic reduction in the broadening at low temperature. Theoretical predictions, the basis for which are calculated collisional excitation rates, indicated stronger excitation, with a steady increase in the broadening as the temperature drops. Due to this disagreement, concerns were raised about the stability...