Urinary bladder paraganglioma is a rare neuroendocrine tumor and nonfunctional bladder paraganglioma is extremely rare and difficult to diagnose due to their non-secreting nature. We report a rare female case of nonfunctional bladder paraganglioma with detailed clinicopathological data and follow-up information. The patient presented with supra-pubic pain. Computed tomography (CT) revealed a 11...

Urinary bladder paraganglioma is a very rare tumor, account for <0.05% of all bladder tumors. They are usually submucosal tumors most commonly located near the urinary bladder trigone. A deeply located urinary bladder paraganglioma may not be seen on cystocope, and pelvic sidewall paraganglioma may mimic urinary bladder paraganglioma. Here we present an extremely rare case of urinary bladder pa...

Malignant hypertension is a complication of hypertension characterized by elevated blood pressure (200mm/140mm Hg), is considered a medical emergency and is rarely secondary to paraganglioma. Malignant hypertension is unique in its relationship to a catecholamine secreting paraganglioma. We present two rare cases of malignant hypertension associated with paraganglioma of tonsil and urinary blad...

We report a case of paraganglioma of the cauda equina and review the MRI features in 11 previously published cases with MRI description. On T1-weighted images, paraganglioma is isointense relative to spinal cord and shows moderate to intense enhancement after Gd-DTPA application, usually with heterogeneous texture. On T2-weighted images, different findings were found. MRI features do not allow ...

Mediastinal paraganglioma is a rare and slow growing neurogenic tumor. Here, we describe a 49-year-old woman with a non-functional posterior mediastinal paraganglioma. Video-assisted thoracoscopic surgery for tumor excision failed due to massive bleeding. The tumor was excised successfully by lateral thoracotomy with bipolar electrocautery 1 week after the first operation. Mediastinal paragangl...

An invasive paraganglioma of the posterior mediastinum caused spinal cord compression in a 31 year old women. Electron microscopic examination of the paraganglioma invading the epidural space revealed numerous dense-cored granules in the cytoplasm of the tumour cells. We are reporting this case to present the ultrastructure of mediastinal paraganglioma, and to call attention to an unusual cause...

The cytotoxic host immune response toward autologous human cancer may be regulated by the immunoregulatory network. Here we show that helper T cells, cloned from peripheral blood lymphocytes that were sensitized in vitro against an autologous human malignant paraganglioma, proliferated against and made interleukin 2 when cocultured with the tumor-associated antigen in the presence of autologous...

paraganglioma of the larynx is a rare neoplasm which mostly arises from supraglottic area.  herein, we report on a 45-year-old woman presented with supraglottic laryngeal paraganglioma.

BACKGROUD Primary pancreatic paraganglioma is an extremely rare extra-adrenal paraganglioma. CASE PRESENTATION We report a case of primary pancreatic paraganglioma undergoing middle segment pancreatectomy in a 42-year-old woman. Histological examination showed that the tumor was composed of well-defined nests of cuboidal cells separated by vascular fibrous septa, forming the classic Zellballe...

Paraganglioma of the urinary bladder is a rare pathologic entity with no definitive histological, immunohistochemical or molecular features to determine its malignant potential. Malignancy is essentially determined by the presence of deep local invasion, invasion of adjacent structures and lymph node or distant metastases. So far, up to 180 cases of paraganglioma have been reported, with <30 be...