Density functional theory has been used to investigate the mechanism and kinetics of the liquid-phase, oxidative carbonylation of toluene to p-toluic acid (C7H8 + CO + /2O2 f p-C7H6COOH + H2O) catalyzed by Rh(III) cations. In toluene solution containing trifluoroacetic acid and dissolved CO, Rh(III) is coordinated to three trifluoroacetate (TFA) anions and two CO molecules as Rh(CO)2(TFA)3. The...

for AICHE 2004 [15C12] Advances in Biocatalysis and Protein Engineering Tailoring Toluene para-Monooxygenase of Ralstonia pickettii PKO1 for Regiospecific Oxidation of Aromatics Using Active Site Engineering A. Fishman, Y. Tao, W. E. Bentley, and T. K. Wood University of Connecticut, Storrs, CT University of Maryland, College Park, MD Oxygenases are promising biocatalysts for performing selecti...

The effects of p-chloromercuribenzoic acid and chloromercuribenzene-p-sulphonic acid on pancreatic islets were studied in vitro. Obese-hyperglycaemic mice were used as the source of microdissected islets containing more than 90% beta-cells. p-Chloromercuribenzoic acid and chloromercuribenzene-p-sulphonic acid stimulated insulin release at concentrations of 0.01mm or above. This stimulation was ...

Introduction An aromatics complex is a combination of process units that can be used to convert petroleum naphtha and pyrolysis gasoline (pygas) into the basic petrochemical intermediates: Benzene Toluene and Xylenes (BTX). Benzene is a versatile petrochemical building block used in the production of more than 250 different products. Ethylbenzene, cumene, and cyclohexane are the most important ...

A cost-effective and environmentally benign benzopyrano-pyrimidine derivative synthesis has been established with the condensation of different salicylaldehyde derivatives, piperidine/morpholine malononitrile, in presence a catalyst containing p-toluene sulphonic acid (PTSA) at 80 °C temperature. This procedure offers new enriched approach for synthesizing derivatives high yields, straightforwa...

the aims of this study were to determine hippuric acid and toluene in urine samples, airborne toluene levels, health effects, and to describe any correlation between specimen samples. seventy-five printing workers exposed to toluene at work (exposed group), and 60 nonexposed people (control group) were studied. study participants were selected from same factories in the different positions. uri...

Experimental and theoretical studies were conducted to investigate the influence of anionic ligands (e.g., CF(3)COO(-), CH(3)SO(3)(-)) on the catalytic activity and selectivity of Rh(III) in the oxidative carbonylation of toluene to toluic acid. The catalyst activity was found to pass through a maximum as the pK(a) of the conjugate Brønsted acid decreases from 4.63 to -2.00, with the maximum ac...

condensation reaction of urea, casein and formaldehyde in the presence of varying proportion of resorcinol under alkaline condition. All the prepared resins were characterized by free-formaldehyde content, free-phenol content, viscosity measurements and infrared spectroscopy (IR). The resin samples were cured isothermally at 120oC using two different curing agents, p-toluene sulphonic acid (PTS...

Urinary and faecal excretion of radioactivity after either an intravenous or oral (1 mg/kg) dose of 35S-labelled Tobias acid (2-naphthylamino, 1-sulphonic acid), a dyestuff intermediate structurally similar to the powerful carcinogen 2-naphthylamine, was studied in rats. The Tobias acid was eliminated from the body within 24 hours of administration, almost exclusively through the urine. TLC-chr...