thyroglossal duct cysts are the most common congenital anomalies in thyroid development, which in less than 1% of cases are malignant. in most cases the diagnosis is made postoperatively. up to now, a few cases have been reported which had been papillary carcinoma. controversies exist concerning its nature and treatment. we present a 30 years old woman with papillary carcinoma of thyroglossal d...

PURPOSE To investigate clinical characteristics and surgical treatment of multifocal papillary thyroid carcinoma. METHODS A total of 648 patients diagnosed with papillary thyroid carcinoma were enrolled, 168 with multifocal papillary thyroid carcinoma. Clinicopathological factors including gender, age at diagnosis, family history of thyroid tumor, multiplicity and bilaterality of tumor, extra...

thyroglossal duct cysts are the most common form of congenital cysts on the neck. the incidence of thyroid papillary carcinoma in thyroglossal duct cyst is less than 1%. in most cases the diagnosis is made postoperatively. we present a 22-year-old female with thyroid papillary carcinoma arising from thyroglossal duct cyst,identified in pathologic study after sistrunk operation.in our case there...

Squamous cell differentiation (SCD) may occur in papillary thyroid carcinoma (PTC) only at metastatic sites. We have studied cytokeratin CK5/6 and P63 along with TTF1 (thyroid transcription factor 1)  and B-Raf (V-Raf murine sarcoma viral oncogene homolog B1) immunohistochemical expression in neck lymph node metastases of thyroid PTC showing SCD. The patient (21-years) presented wit...

Parotid metastasis originated from papillary thyroid carcinoma is extremely rare, especially as the first presentation of the disease. We present a 70-year-old man with a history of painless swelling in the right side of the neck. He was evaluated for parotid tumor and histopathologic examination revealed a poorly differentiated carcinoma in the parotid gland with suspicion of thyroid origin. T...

Background & objective: papillary thyroid cancer is the most common cancer of thyroid accounting for 75%-85% of all thyroid malignancies. Recently, β-catenin has been determined to play a role in clinical course of human epithelial cancers. This study was designed to reveal the association of β-catenin marker and papillary thyroid carcinoma behavior.<b...

papillary carcinoma of the thyroid constitutes 80% of thyroid malignancies in adults. females are affected at least twice as often as males. it metastasizes to distant sites very rarely, but to the cervical nodes quite often. occasionally metastatic lymph node enlargement is the sole presenting feature. t.3.6.7 the tumor is slow growing and sometimes the patient has good survival even in spite ...

Background: Breast cancer is the most commonly diagnosed and the leading cause of cancer death among females worldwide. The rate of breast cancer incidence among Iranian women is 17% of all cancers, it has been ranked first in Iran. This study aimed to investigate the factors affecting axillary lymph node involvement in female patients with breast cancer. Methods: A cross-sectional study was c...

This study sought to investigate the correlations of V-raf murine sarcoma viral oncogene homolog B1 (BRAF) gene mutations with the clinicopathologic features of papillary thyroid carcinoma and central lymph node metastasis. We retrospectively analyzed the 2-year medical records of patients who underwent surgery for papillary thyroid carcinoma. After screening, the records of 126 patients who me...

Papillary carcinoma of the thyroid constitutes 80% of thyroid malignancies in adults. Females are affected at least twice as often as males. It metastasizes to distant sites very rarely, but to the cervical nodes quite often. Occasionally metastatic lymph node enlargement is the sole presenting feature. t.3.6.7 The tumor is slow growing and sometimes the patient has good survival even in s...