Mestastatic prostate cancer cells (MPCCs) frequently metastasize to bone, which is a “favorite soil” for colonization and proliferation of MPCCs. Prostate cancer bone mestastasis is tightly associated with tumor-induced bone lesions, most commonly caused from the etiological imbalance between osteoblastic bone formation and osteoclastic bone resorption, and from the anti-tumor immune response. ...

Objective(s): BONENAVI, a computer-aided diagnostic system, is used in bone scintigraphy. This system provides the artificial neural network (ANN) and bone scan index (BSI) values. ANN is associated with the possibility of bone metastasis, while BSI is related to the amount of bone metastasis. The degree of uptake on bone scintigraphy can be affected by the type of bone metastasis. Therefore, t...

introduction: almost all malignant tumors have the potential to eventually produce bone metastasis. the aim of the current study was to report the distribution pattern and imaging characteristics of bone metastases detected by conventional whole body bone scintigraphy in patients with different types of malignancies and to assess their relationship with the complaint of bone pain. methods: as ...

objective(s): bonenavi, a computer-aided diagnostic system, is used in bone scintigraphy. this system provides the artificial neural network (ann) and bone scan index (bsi) values. ann is associated with the possibility of bone metastasis, while bsi is related to the amount of bone metastasis. the degree of uptake on bone scintigraphy can be affected by the type of bone metastasis. therefore, t...

Most deaths from solid cancers occur as a result of secondary metastasis to distant sites. Bone is the most frequent metastatic site for many cancer types and can account for up to 80% of cancer-related deaths in certain tumours. The progression from a discrete solid primary tumour to devastating and painful bone metastases is a complex process involving multiple cell types and steps. There is ...

This case report describes an uncommon presentation of lung adenocarcinoma, which appeared as a skull mass. While not the first reported in medical literature, it is still rare occurrence for adenocarcinoma to present this manner. focuses on clinical and treatment elderly male patient who had progressively enlarging painful The initial imaging revealed about 5 cm soft tissue mass at dorsal midl...

Corresponding author: Yoon-Hee Kim, M.D., Ph.D., Department of Anesthesiology and Pain Medicine, Chungnam National University School of Medicine, Munhwa-ro, Jung-gu, Daejeon 301-721, Korea. Tel: 82-42-280-7841, Fax: 82-42-280-7968, E-mail: [email protected] This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:// creative...

introduction: the aim of the present study was to evaluate the efficacy and safety profile of bone palliative therapy following administration of 153sm-edtmp in patients with intractable metastatic bone pain. methods: sixteen patients (9 male, 7 female) aged 29-80 years (57.3±16.7 years) with severe metastasis-related bone pain resistant to analgesic medications were enrolled in the study. all...

metastatic survey of the patients with known primary malignancies with bone scan is one of the most common studies in nuclear medicine. unfortunately the conventional planar bone scan has a very low specificity for differentiating benign from malignant lesions especially in the spinal column. in this study, we compared the specificity of spect imaging and conventional planar bone scan. we studi...