نتایج جستجو برای: p88
تعداد نتایج: 83 فیلتر نتایج به سال:
Volcano arabica coffee is one of the best derived from Gayo Highlands, Aceh Province, Indonesia. That was cultivated in a volcanic region, therefore as known volcano coffee. Several varieties were included Borbor, Timtim, and P88. low caffeine with taste exceeding Blue Mountain Jamaica which determined using sensory assessment. This study aims to conduct assessment variety analytical hierarchy ...
Abstract Background Nesprins are proteins encoded by synaptic nuclear envelope (SYNE)–1 and –2 genes, that concur, together with lamin A/C emerin, to function. Almost 140 disease–related variants were identified, mostly resulting in central nervous system skeletal muscle disorders; only a few associated cardiomyopathy, relatively late onset no specific arrhythmic profile. Purpose To describe ca...
The Helicobacter pylori VacA toxin is an 88-kDa secreted protein that causes multiple alterations in mammalian cells and is considered an important virulence factor in the pathogenesis of peptic ulcer disease and gastric cancer. We have shown previously that a VacA mutant protein lacking amino acids 6 to 27 (Delta6-27p88 VacA) is able to inhibit many activities of wild-type VacA in a dominant-n...
Turnip crinkle virus (TCV) (family Tombusviridae, genus Carmovirus) is a positive-sense RNA virus containing a 4054-base genome. Previous results indicated that insertion of Hairpin 4 (H4) into a TCV-associated satellite RNA enhanced replication 6-fold in vivo (Nagy, P., Pogany, J., Simon, A. E., 1999. EMBO J. 18:5653-5665). A detailed structural and functional analysis of H4 has now been perfo...
The yeast UBC9 gene encodes a protein with homology to the E2 ubiquitin-conjugating enzymes that mediate the attachment of ubiquitin to substrate proteins [1]. Depletion of Ubc9p arrests cells in G2 or early M phase and stabilizes B-type cyclins [1]. p18(Ubc9), the Xenopus homolog of Ubc9p, associates specifically with p88(RanGAP1) and p340(RanBP2) [2]. Ran-binding protein 2 (p340(RanBP2)) is a...
In the literature on graphical models, there has been increased attention paid to the problems of learning hidden structure (see Heckerman [H96] for a survey) and causal mechanisms from sample data [H96, P88, S93, P95, F98]. In most settings we should expect the former to be di cult, and the latter potentially impossible without experimental intervention. In this work, we examine some restricte...
PURPOSE Over the past two decades, there has been significant interest in targeting HER-2/neu in immune-based approaches for the treatment of HER-2/neu+ cancers. For example, peptide vaccination using a CD8 T cell-activating HER-2/neu epitope (amino acids 369-377) is an approach that is being considered in advanced phase clinical trials. Studies have suggested that the persistence of HER-2/neu-...
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