A B S T R A C T Introduction: In an oddball experiment, the context in which novel stimuli are presented affects characteristics of novelty P3, i.e. as long as there is a difficult task in which the difference between standard and target stimuli is small, recurrent presentation of a highly discrepant stimulus can lead to P300 highly similar to novelty P3. Effect of stimulus properties on P300 h...

Introduction: Evoked potentials arisen by stimulating the brain can be utilized as a communication tool  between humans and machines. Most brain-computer interface (BCI) systems use the P300 component,  which is an evoked potential. In this paper, we evaluate the use of the hidden Markov model (HMM) for  detection of P300.  Materials and Methods: The wavelet transforms, wavelet-enhanced indepen...

OBJECTIVE The P300 event-related potential shows anterior P300 increases on NoGo tasks (target stimulus=withhold response) relative to Go tasks (target stimulus=commit response). This 'NoGo anteriorization' has been hypothesized to reflect response inhibition. However, silent-count tasks show similar P300 anteriorization. The P300 anteriorization on silent-count tasks relative to Go tasks canno...

OBJECTIVE To characterize downstream effectors of p300 acetyltransferase in the myocardium. BACKGROUND Acetyltransferase p300 is a central driver of the hypertrophic response to increased workload, but its biological targets and downstream effectors are incompletely known. METHODS AND RESULTS Mice expressing a myocyte-restricted transgene encoding acetyltransferase p300, previously shown to...

Background: The P300 components of auditory event related potentials (ERPs) are objective measures related to information and cognitive processing. Objectives: To assess P300 ERPs in female patients with fibromyalgia (FM) in comparison with healthy age matched controls. To investigate the relationship between P300 potentials and pain threshold levels of patients, and subsequent effect of sertra...

Acetylation of proteins by p300 histone acetyltransferase plays a critical role in the regulation of gene expression. The prior discovery of an autoacetylated regulatory loop in the p300 histone acetyltransferase (HAT) domain prompted us to further explore the mechanisms of p300 autoacetylation. Here we have described a kinetic and mass spectrometric analysis of p300 HAT autoacetylation. The ra...

Background: Scant and equivocal research exists examining the effects of button-pressing on P300. Button-pressing may decrease P300 latency and amplitude. The melding of motor potentials and P300 may also confound studies of P300 topography, such as studies of temporal scalp-area asymmetries in schizophrenia. Method: P300 was measured on button-press and silent-count tasks in control subjects. ...

BACKGROUND The P300 components of auditory event related potentials (ERPs) are objective measures related to information and cognitive processing. OBJECTIVES To assess P300 ERPs in female patients with fibromyalgia (FM) in comparison with healthy age matched controls. To investigate the relationship between P300 potentials and pain threshold levels of patients, and subsequent effect of sertra...