Abstract Introduction Sleep disorders have been considered the forgotten dimension of COPD; however, as high percentage patients are affected, they clinically important. This study aimed to determine sleep quality and severity dyspnoea in Chronic Obstructive Pulmonary disease(COPD) evaluate relationship between quality. Method A retrospective analysis 107 attending a specialist COPD clinic UK t...

In vertebrates, retinal progenitor cells (RPCs) are specified at the end of the gastrulation within the anterior neural plate (ANP) as a single domain called the eye field. From that single domain, positioned medially within the ANP, the RPCs give rise to two optic vesicles, positioned more laterally. How this dramatic morphogenetic remodelling occurs is not well understood. We will show that s...

agus, stomach, pre-umbilical intestine, post-umbilical intestine, hindgut), but overall it was significantly shorter compared with controls. In talpid3 gut, although neural crest-derived ENS precursors (shown with HNK-1 immunohistochemistry) and TuJ1-positive enteric neurons were distributed along the length of the gut, similar to controls, there were dramatic differences in their patterning ac...