نتایج جستجو برای: oxidative phosphorylation respiration
تعداد نتایج: 257783 فیلتر نتایج به سال:
Streptolydigin interferes with oxidative phosphorylation in rat liver mitochondria. The agent acts primarily as an uncoupler of respiration-associated phosphorylation but also impairs respiration to various degrees depending on the substrate. Streptolydigin partially inhibits electron flow at a point past the cytochrome b and prior to the cytochrome c reduction site. Streptolydigin also inhibit...
Exogenous and endogenously generated reduced pyridine nucleotides caused marked stimulation of O(2) uptake when added to treponemal cell-free extracts, which indicated that terminal electron transport was coupled to the consumption of O(2). Oxidation of reduced nicotinamide adenine dinucleotide (NADH) was shown to correlate stoichiometrically with O(2) reduction, suggesting that NADH was being ...
Accumulation of Ca2+ (+ phosphate) by respiring mitochondria from Ehrlich ascites or AS30-D hepatoma tumor cells inhibits subsequent phosphorylating respiration in response to ADP. The respiratory chain is still functional since a proton-conducting uncoupler produces a normal stimulation of electron transport. The inhibition of phosphorylating respiration is caused by intramitochondrial Ca2+ (+...
Stimulation of mitochondrial respiration by physiological concentrations of Ca2+ was studied to determine which components of oxidative phosphorylation are affected by Ca2+. The kinetic dependence of the respiratory chain, phosphorylation subsystem and proton leak on the mitochondrial membrane potential in isolated rat heart mitochondria respiring on 2-oxoglutarate or succinate was measured at ...
The article provides information on the effect of pesticides - butylcaptax and droppa respiration oxidative phosphorylation liver mitochondria in rat rats their embryos. It has been shown that reduce oxidation succinate α-ketoglutarate V4*, V3 V dnf states drug conjugation pregnant animals most significant inhibition ADF formation respiratory chain fatal maternal occurs via NAD-dependent pathwa...
The finding that oxidative phosphorylation is uncoupled by nitroand halophenols (l-3) has led a number of investigators (4-10) to examine the effect of a physiological halophenol, thyroxine, on this process. Uncoupling of phosphorylation from respiration has been observed following addition of thyroxine and related compounds to suspensions of mitochondria (4-8) as well as in mitochondria isolat...
The cytosolic factors that influence mitochondrial oxidative phosphorylation rates are relatively unknown. In this report, we examine the effects of phosphoenolpyruvate (PEP), a glycolytic intermediate, on mitochondrial function. It is reported here that in rat heart mitochondria, PEP delays the onset of state 3 respiration in mitochondria supplied with either NADH-linked substrates or succinat...
The yield of oxidative phosphorylation in isolated tomato fruit mitochondria depleted of free fatty acids remains constant when respiratory rates are decreased by a factor of 3 by the addition of n-butyl malonate. This constancy makes the determination of the contribution of the linoleic acid-induced energy-dissipating pathway by the ADP/O method possible. No decrease in membrane potential is o...
ABSTRACT Mitochondria provide cellular energy through oxidative phosphorylation, and thus temperature-induced constraints on mitochondrial function may be crucial to animal aerobic scope thermal tolerance. Here, we report the effect of temperature in range 5–30°C respiration rates isolated cardiac mitochondria from rainbow trout (Oncorhynchus mykiss) studied by high-resolution respirometry spec...
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