background bladder reconstruction in the pediatric population is challenging for many reasons, including perioperative complications and readmissions. objectives on a national scale, determine readmission rates at 30, 60 and 90 days after bladder reconstruction in a pediatric population over a 7-year period, evaluating the influence of hospital and patient-specific variables. patients and metho...

The matrix metalloproteinases (MMPs), in particular the gelatinases (MMP-2 and MMP-9) have been associated with tumor cell invasion and metastasis in many human cancers. Here we examined the expression of proMMP-2 (gelatinase A) and proMMP-9 (gelatinase B) proteins in the cellular component of bladder washes obtained from 65 patients. Twenty-six patients had active bladder cancer, 24 had a hist...

To study the relative importance of neurogenic factors in detrusor contractility and to relate a total bladder in vitro contractility model to a previously described bladder wall strip model, active intravesical pressure values were compared in situ and in vitro in eight male guinea pigs. In situ, the active pressure was measured in spontaneous isometric and non-isometric micturition contractio...

Hypothesis / aims of study Fesoterodine is a relatively novel antimuscarinic agent for the treatment of overactive bladder (OAB) [1]. When administered orally, fesoterodine is rapidly and extensively converted to its active metabolite, 5-hydroxymethyl tolterodine (5-HMT), which is also an active metabolite of tolterodine [2]. Our recent study with radioligand binding assay has shown that fesote...

Background & Aims: In the western countries, bladder cancer is the fourth and eighth common cancer in males and females, respectively, and like other cancers it has been significantly increasing in last years. The aim of this study was to find out the epidemiology of bladder cancer in Fars province /Iran during 2003-2008 according to cancer registry data system. Methods: In this epidemiological...

A 68-year-old man developed progressive weakness over 4 weeks. He had difficulty rising from a low position, climbing stairs, and raising his arms overhead, particularly toward evenings. no pain, sensory, or bowel bladder symptoms, denied ptosis, diplopia, dysphagia, dyspnea. mild unintentional weight loss but fevers. His medical history revealed eczema active smoking (50 pack-years). There was...

conclusions gastric pouch is a suitable segment for bladder cystoplasty and neobladder. continence is mostly related to the capacity of pouch. results postoperative complications were rare. continence was defined as bladder capacity over 400 ml. their follow-up period ranged from five months up to writing the article. one of the studied cases is still alive and awaiting renal transplantation. m...