The occurrence of more than two ova from the same follicle (polyovular follicle) in humans has been observed. In this case report there was a high frequency of conjoined oocytes retrieved with individual zona pellucida (40% of oocytes retrieved, 4.3% of mature follicles) from women with polycystic ovary syndrome (PCOS). We may have to be more aware of the risk of multiple pregnancies in inferti...

OBJECTIVE To assess the effect of unilateral oophorectomy (UO) by assessing ovarian reserve (OVR) and the response to gonadotropin stimulation in women with UO undergoing in vitro fertilization (IVF) compared with the response of the ipsilateral ovary of women without UO. DESIGN Historical cohort study. SETTING Academic fertility clinic. PATIENT(S) Fifty-one women with single ovary compar...

lead is an ubiquitous environmental toxin that induces a broad range of physiological biochemical, and behavioral dysfunctions. in this study, we examined the pathologic effects of lead acetate in nmri mouse ovarian tissue and the protective role of antioxidant l-cysteine, against the induced damage. we used lead acetate at a dose of 10 mg/kg, and l-cysteine at a dose of 200 mg/kg. both drugs w...

this present study was conducted to evaluate the effects of dietary inclusion of 4, 8 and 12 g kg-1 phytogenic feed additives mixture on performance, egg quality, ovary parameters, serum biochemical parameters and yolk trimethylamine level in laying hens. the results of experiment have shown that egg weight was increased by supplementation of 12 g kg-1 feed additive whereas egg production, feed...

Ovary development is a complex process involving numerous genes. A well-developed ovary is essential for females to keep fertility and reproduce offspring. In order to gain a better insight into the molecular mechanisms related to the process of mammalian ovary development, we performed a comparative transcriptomic analysis on ovaries isolated from infant and adult mice by using next-generation...

Purpose To identify which methods used in the assessment of the ovarian reserve are exclusive or complementary to identify the best response to follicle development. Methods Retrospective cohort study, involving patients undergoing assisted reproduction treatment at the Instituto de Medicina Reprodutiva e Fetal, from April 2009 to July 2014. Age, biochemical tests, and ultrasound were assessed....

Notch signaling directs cell fate during embryogenesis by influencing cell proliferation, differentiation, and apoptosis. Notch genes are expressed in the adult mouse ovary, and roles for Notch in regulating folliculogenesis are beginning to emerge from mouse genetic models. We investigated how Notch signaling might influence the formation of primordial follicles. Follicle assembly takes place ...

Follicle growth in the mammalian ovary is coordinately controlled by multiple factors to sustain periodic ovulation. In this study, we investigated the role of progesterone on follicle growth in the mouse ovary. As the concentration of progesterone changes during the estrus cycle, we cultured the sliced mouse ovary in a medium containing 10 ng/ml, 100 ng/ml, and 1 μg/ml progesterone. Progestero...

In the present study, we cloned full-length cDNAs for epidermal growth factor (EGF), EGF receptor (EGFR) and three truncated forms of EGFR (EGFR15, 12 and 8) from the zebrafish ovary. Zebrafish EGF was predominantly expressed in the ovary and testis, while EGFR and its truncated forms were highly expressed in all tissues examined except the liver. In the ovary, the expression of EGF seemed to b...

Paracrine signalling between the oocyte and its surrounding somatic cells is fundamental to the processes of oogenesis and folliculogenesis in mammals. The study of animal models has revealed that the interaction of granulosa cell-derived kit ligand (KL) with oocyte and theca cell-derived c-Kit is important for multiple aspects of oocyte and follicle development, including the establishment of ...