Growing evidence has shown that hepatic oval cells, also named liver progenitor cells, play an important role in the process of liver regeneration in various liver diseases. Oval cell proliferation has been reported in hepatitis B virus (HBV)-associated hepatocellular carcinoma (HCC) and chronic liver disease. Studies have found expression of HBV surface and core antigens in oval cells in the l...

A s is widely appreciated by all medical and surgical specialties, atrial fibrillation is the most common significant cardiac arrhythmia seen in practice; approximately 5 to 7 million patients in the United States have atrial fibrillation, with the numbers expected to increase to approximately 16 million by 2050 (1), and there are 200,000 to 250,000 new cases each year. Although symptoms vary w...

AIM To evaluate ex vivo the bond strength and adaptation of fibre posts with oval and circular cross sections luted in oval canals with post spaces prepared using dedicated drills or ultrasonic tips. METHODOLOGY Forty extracted premolars with oval canals were root filled, then randomly divided into four groups according to the post space preparation device and the shape of the luted fibre pos...

Forame Oval é um orifício localizado no septo interatrial, formado pela fusão dos septum primum e secundum dispensável embriologicamente, pois permite passagem sanguínea do átrio direito para o esquerdo, através da diferença de pressão. Contudo, em 25 a 35% população adulta, mesmo torna-se patente, gerando uma condição patológica. O objetivo trabalho foi realizar revisão literatura não sistemat...

We examined the response of murine oval cells, that is, the putative liver progenitor cells, to acetaminophen. Female C57BL/6J mice were injected intraperitoneally with varying doses of N-acetyl-paraaminophen (APAP) (250, 500, 750, and 1,000 mg/kg of weight) and sacrificed at 3, 6, 9, 24, and 48 hours. In preliminary studies, we showed that anticytokeratin antibodies detected A6-positive cells ...

Introduction Recently, MITRE/SEDI developed a new draft component schema for OVAL to support interaction with the Trusted Platform Module (TPM). At a basic level, this is no different than most other component schemas: it simply expands OVAL's ability to collect system state information into a new component. However, because of some of the unique features of the TPM, this expansion of OVAL also...

An electron microscopic, immunocytochemical, and enzyme cytochemical analysis of the previously established oval cell lines OC/CDE 6 and OC/CDE 22 was performed to characterize the phenotype and differentiation patterns of long-term cultures of oval cells. It was found that alpha-fetoprotein, albumin, and cytokeratin 19 are present in all cultured cells. This indicates that oval cells constitut...

Hepatic oval cells are considered to be facultative hepatic stem cells (HSCs) that differentiate into hepatocytes and cholangiocytes in severely injured liver. Hepatic oval cells have also been implicated in tumorigenesis. However, their nature and origin remain elusive. To isolate and characterize mouse oval cells, we searched for cell surface molecules expressed on oval cells and analyzed the...