نتایج جستجو برای: outer membrane vesicle

تعداد نتایج: 454546  

Journal: :Journal of bacteriology 2006
Amanda J McBroom Alexandra P Johnson Sreekanth Vemulapalli Meta J Kuehn

It has been long noted that gram-negative bacteria produce outer membrane vesicles, and recent data demonstrate that vesicles released by pathogenic strains can transmit virulence factors to host cells. However, the mechanism of vesicle release has remained undetermined. This genetic study addresses whether these structures are merely a result of membrane instability or are formed by a more dir...

Journal: :The Journal of general virology 1997
M C Ruiz M J Abad A Charpilienne J Cohen F Michelangeli

It has previously been shown that trypsinized triple-layered particles of rotavirus induce destabilization of liposomes and membrane vesicles in the absence of Ca2+, a condition which leads to solubilization of the outer capsid proteins of the virus. In this work, we have studied the relationship between outer capsid solubilization and permeabilization of membrane vesicles, monitoring particle ...

2017
Eloise J O'Donoghue Natalie Sirisaengtaksin Douglas F Browning Ewa Bielska Mohammed Hadis Francisco Fernandez-Trillo Luke Alderwick Sara Jabbari Anne Marie Krachler

Outer membrane vesicles are nano-sized microvesicles shed from the outer membrane of Gram-negative bacteria and play important roles in immune priming and disease pathogenesis. However, our current mechanistic understanding of vesicle-host cell interactions is limited by a lack of methods to study the rapid kinetics of vesicle entry and cargo delivery to host cells. Here, we describe a highly s...

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