Osteopenia, or low bone density, is a chronic condition characterized by decreased calcification, density, and mass of bones, it represents a major health issue. Nutrition plays a key role in the prevention and management of this condition. Among different nutritional supplementation, curcumin is characterized by a wide spectrum of pharmacological activities, also with potential reference to th...

Background and aims: Transfer of CD4CD45RB T cells into semi syngeneic immunodeficient mice represents a model of inflammatory bowel disease (IBD). As patients with IBD often suffer from osteopenia, we studied if this T cell transfer in mice results in osteopenia in addition to colitis, and if treatment with osteoprotegerin (OPG) has effects on the bone mineral density of T cell transferred mic...

background: osteopenia is common problem in premature infants. low-birth weight babies do not receive adequate amounts of calcium and phosphorus through breast feeding. this study examines the effect of calcium and phosphorus supplements on osteopenia in premature infants. methods: this clinical trial included 42 premature infants hospitalized at razi hspital in kermanshah. all the babies had a...

INTRODUCTION Loss of bone due to disuse osteopenia remains an unsolved and debilitating problem. While some current therapies rely on weightbearing activities to promote new bone growth, disuse osteopenia often occurs in situations in which weight bearing or mechanical loading of bone is impractical, e.g. in bedridden or mobility limited individuals or in microgravity conditions. Hence, new the...

It is not widely appreciated how deleterious prolonged periods of non-weight-bearing are to skeletal integrity. Rates of decline in humans exposed to prolonged spaceflight, for example, are about 10-fold greater than those observed in postmenopausal women and are associated with a significant loss of bone strength. New data on the efficacy of muscle contraction independent of weight bearing in ...

BACKGROUND Although bone mineral density (BMD) testing to screen for osteoporosis (BMD T score, -2.50 or lower) is recommended for women 65 years of age or older, there are few data to guide decisions about the interval between BMD tests. METHODS We studied 4957 women, 67 years of age or older, with normal BMD (T score at the femoral neck and total hip, -1.00 or higher) or osteopenia (T score...

osteopenia of prematurity (oop) is a preventable disease. improved survival of premature newborns is associated with an increased incidence of oop. the purpose of this study was to compare the prophylactic effects of two low doses of vitamin d (200 and 400 iu/day) on the clinical, biochemical and radiological indices of the rickets of prematurity. in a randomized clinical trial, 60 preterm newb...