Actinomycosis is occasionally an opportunistic infection occurrence in patients with osteoradionecrosis (ORN). A retrospective study (1992-97) of 50 patients with ORN of the jaws was done to evaluate the incidence and its clinical significance in the management of ORN. Actinomycosis was diagnosed in 12% of ORN cases. In 36 of the 50 patients including five cases of actinomycosis, the ORN was co...

Object Relationship Notation (ORN) is a declarative scheme that allows a variety of common relationship types to be conveniently specified to a Database Management System (DBMS), thereby allowing their semantics to be automatically enforced by the DBMS. ORN can be integrated into any data model that represents binary associations or DBMS that implements them. In this paper, we give a brief desc...

BACKGROUND Mandibular osteoradionecrosis (ORN) is a potentially debilitating complication of ionizing radiotherapy, with an incidence-reported to range from 5% to 15%. ORN is most commonly defined as exposed, irradiated, nonhealing bone of at least 2 to 3 months duration without evidence of tumor recurrence. Although this complication often occurs within the first 6 to 12 months following radio...

Renal arginase activity is a potent source of ornithine (Orn) for polyamine synthesis. Ornithine decarboxylase (ODC) was localized along the mouse and rat nephron by incubating viable nephron segments isolated by microdissection from collagenase-treated kidneys with or withoutd,l-2-(difluoromethyl)ornithine (DFMO), a selective inactivator of ODC. Tubules from either control or DFMO-treated anim...

The olfactory system is divided into processing channels (glomeruli), each receiving input from a different type of olfactory receptor neuron (ORN). Here we investigated how glomeruli combine to control behavior in freely walking Drosophila. We found that optogenetically activating single ORN types typically produced attraction, although some ORN types produced repulsion. Attraction consisted l...

The effectiveness of the antimicrobial peptide maximin-4, the ultrashort peptide H-Orn-Orn-Trp-Trp-NH(2), and the lipopeptide C(12)-Orn-Orn-Trp-Trp-NH(2) in preventing adherence of pathogens to a candidate biomaterial were tested utilizing both matrix- and immersion-loaded poly(2-hydroxyethyl methacrylate) (poly(HEMA)) hydrogels. Antiadherent properties correlated to both the concentration rele...

It is noteworthy that colon cancer the fourth place in new cases and fifth mortalities according to global statistics 2018. Tumorigenesis displays specific correlation with metabolic alterations. A variety of metabolites, including ornithine (Orn), are related sources disease information retrieval human metabolome database. The regulation Orn pathway a key link survival cells. In this study, pl...

BACKGROUND Osteoradionecrosis (ORN) defines exposed irradiated bone, which fails to heal over a period of 3-6 months without evidence of residual or recurrent tumor. In the previous decades, a staging and treatment protocol suggested by Marx, has dominated the approach to ORN. However, recently this paradigm is shifting. The purpose of this study was to evaluate our institutional experience in ...

BACKGROUND Osteoradionecrosis (ORN) is a critical complication after carbon ion (C-ion) or photon radiotherapy (RT) for head and neck tumors. However, the risk factors for ORN after C-ion RT remain unclear. Therefore, the present study aimed to investigate the effects of the dose-volume relationship on and risk factors for ORN development after C-ion RT. We, however, focused on the maxillary bo...

Osteoradionecrosis (ORN) is a serious complication of radiation therapy, which was first described by Ewing in 1926.(1) While ORN of the mandible has been commonly reported, any radiated bone has potential to be effected. While ORN of the temporal bone is a relatively rare and indolent disorder, it can have devastating sequelae. It typically presents with chronic otomastoiditis. This is, to the...