Salivary amylase binds specifically to a number of oral streptococcal species. This interaction may play an important role in dental plaque formation. Recently, a 585-bp gene was cloned and sequenced from Streptococcus gordonii Challis encoding a 20.5-kDa amylase-binding protein (AbpA). The goal of this study was to determine if related genes are present in other species of oral streptococci. B...

Oral cancers are attributed to a number of causal agents including tobacco, alcohol, human papillomavirus (HPV), and areca (betel) nut. Although betel nut chewing has been established as an independent cause of oral cancer, the mechanisms of carcinogenesis are poorly understood. An investigation was undertaken to evaluate the influence of betel nut chewing on the oral microbiome and oral premal...

The oral cavity harbors a diverse community of microbes that are physiologically unique. Oral microbes that exist in this polymicrobial environment can be pathogenic or beneficial to the host. Numerous oral microbes contribute to the formation of dental caries and periodontitis; however, there is little understanding of the role these microbes play in systemic infections. There is mounting evid...

abstract introduction. cardiovascular disease is the most common cause of death in developed counteries and it’s morbidity and mortality is also increasing in asia. hypertension, hyperlipidemia and smoking are majore risk factors of atherosclerosis. in recent years infectious agents such as clamidia pneumoniae, helicobacter pylori and dental flora infections seems to be effective in development...

background: anti-microbial agents have been used as a chemotherapeutic agent to improve oral health. this in vitro study was carried out to determine antimicrobial efficacy of different toothpastes and mouthrinses against the oral pathogens.     methods: a total of five toothpastes and five mouthrinses were tested for their antimicrobial activity against three oral pathogens namely, streptococc...

When undergoing chemotherapy, it is easy for patients to develop an intraoral disorder as an adverse event. If intraoral disorder worsens, we cannot but stop chemotherapy. In this situation, oral bacteria are often detected in the blood. The goal of perioperative oral function management (POMF) during chemotherapy is to allow chemotherapy to proceed smoothly while maintaining the intraoral envi...

In the present study we investigated the incidence of bacteriocins produced by 236 lactic acid bacteria (LAB) food isolates against pathogenic or opportunistic pathogenic oral bacteria. This set of LAB contained several strains (≥17%) producing bacteriocins active against food-related bacteria. Interestingly only Streptococcus macedonicus ACA-DC 198 was able to inhibit the growth of Streptococc...

Streptococcus oligofermentans, an oral commensal, inhibits the growth of the dental caries pathogen Streptococcus mutans by producing large amounts of hydrogen peroxide. Therefore, it can be a potential probiotic for oral health. Here we report the complete genome sequence of S. oligofermentans strain AS 1.3089.

Streptococcus salivarius strains are significant contributors to the human oral microbiome. Some possess unique fimbriae that give them the ability to coaggregate and colonize particular oral structures. We present here the complete genomes of Streptococcus salivarius Lancefield K-/K+ strains ATCC 25975 and ATCC 27945, which can and cannot, respectively, produce fimbriae.