this study was performed to identify endometrial cancer risk factors. in a case series study on 1989-1996 , we assessed endometrial cancer in 52 patients whose age range was 32-80 years, with 73% over fifty years. obesity was seen in 68% at time of cancer detection , and 69% were in the postmenopausal age, with a history of late menopause in 21%. as a matter of parity 13% were nulliparous, and ...

The relationship of contraceptive history to diagnostic category of amenorrhoea was analysed in 131 consecutively investigated cases of secondary amenorrhoea. Amenorrhoea occurred in 52 patients immediately after discontinuing the oral contraceptive. Twenty-two had had amenorrhoea before oral contraceptive treatment and 23 patients before the episode of non-contraceptive-related amenorrhoea inv...

BACKGROUND Oral contraceptives are commonly used by women athletes. However, their effect on athletic performance is unclear. OBJECTIVES To examine the effects of a moderate dose, triphasic oral contraceptive on measures of athletic performance in highly trained women athletes. METHODS This is a double blind, placebo controlled trial in 14 women with ovulatory menstrual cycles and maximal a...

The relationship between two menstrual cycle phases and cardio respiratory fitness in athletes on oral contraceptives and not on oral contraceptives was assessed in a pilot study. Twelve endurance-trained college cross country runners underwent maximal oxygen consumption treadmill testing, during the late follicular/ovulatory phase and late luteal/premenstrual phase of their menstrual cycle. No...

OBJECTIVE To estimate real-life effectiveness of oral contraceptive pills by progestogen, length of pill-free interval, and body mass index while focusing on the effect of progestogens with a long half-life and on 24-day oral contraceptive pills regimens. METHODS Outcome data from 52,218 U.S. participants in the International Active Surveillance of Women Taking Oral Contraceptives—a large, pr...

BACKGROUND Consistent with its effect on gastric emptying, exenatide, an injectable treatment for type 2 diabetes, may slow the absorption rate of concomitantly administered oral drugs resulting in a decrease in maximum concentration (Cmax). This study evaluated the drug interaction potential of exenatide when administered adjunctively with oral contraceptives, given their potential concomitant...

Primary care physicians often prescribe contraceptives to women of reproductive age with comorbidities. Novel delivery systems (e.g., contraceptive patch, contraceptive ring, single-rod implantable device) may change traditional risk and benefit profiles in women with comorbidities. Effective contraceptive counseling requires an understanding of a woman's preferences and medical history, as wel...

OBJECTIVE To evaluate the motivators and barriers to the use of the combined oral contraceptive pill among Hong Kong women. METHODS The Family Planning Association of Hong Kong commissioned the ESDlife to launch an online survey and invited its female members aged 18 to 45 years who had used contraceptives in the past 12 months to participate in this survey. The online survey was posted on th...

BACKGROUND Previous studies convincingly showed an increase in risk of breast cancer associated with current or recent use of oral contraceptives from the 1960s to 1980s. The relation of contemporary oral contraceptive formulations to breast cancer risk is less clear. METHODS We assessed lifetime oral contraceptive use and the specific formulations used among 116,608 female nurses ages 25 to ...

OBJECTIVE To assess the association between condom use and oral contraceptive consumption and the risk of cervical intraepithelial neoplasia (CIN). METHODS A cross-sectional study was conducted in Perth clinics. A total of 348 women responded to the structured questionnaire. Information sought included demographic and lifestyle characteristics such as the use of condom for contraception, cons...