abstract background and aim: increased rate of micronucleus in buccal mucosa cells and its correlation with carcinogenesis is worth consideration. recently, occupation in dental laboratories has been proposed as a predisposing factor. therefore, the present study aimed to evaluate the effect of occupational exposure on buccal mucosa cells of dental laboratory technicians. materials and methods:...

background: oral cancer has emerged as a significant cause of global public health concern. if a cancerous lesion is diagnosed in primary stages, the survival rate would be higher. thus, the aim of this study was to evaluate knowledge, attitude and practice of general dentist regarding oral cancer in sari, iran. methods: this cross sectional analytical study was performed on general dentists of...

oral submucous fibrosis is chronic progressive condition of oral cavity. the condition is well recognized for its malignant potential. usually the disease initiates with redness, blistering, and ulceration inside the mouth. it is characterized by progressive fibrosis of submucosal tissue. the pathogenesis of oral submucous fibrosis is not well understood. betelquid chewing is the major etiologi...

immunohistochemical demonstration of tumor-associated markers may be valuable as an adjunct to conventional histology for determination of malignancy development in oral mucosal diseases. accordingly, the present study determined the distribution of some important tumor markers such as heat shock proteins (hsp), fibroblast growth factors (fgf) and transferrin receptors (tf-r) in 22 samples of p...

introduction :  despite  recent  advances  in  treatment  of  oral  cancer,  it  still causes high rates of mortality and morbidity worldwide. delays in diagnosis and treatment of these cancers greatly affect the prognosis.  this study aimed to assess the treatment delay and its relation to diagnostic delay among oral cancer patients in tehran, iran. materials and methods : we studied 100 patie...

background: oral mucositis (om) remains the most common side effect of chemotherapy affects negatively on patients' quality of life. subjects and methods : convenience samples of patients who received chemotherapy were followed from first or second cycle of chemotherapy until om occurrence. we reviewed 75 female patients with breast cancer who received chemotherapy with mean age (47.2 sd ± 8.62...

the cancer of oral cavity is related to lesions of mucous membrane of tongue and gum that can be treated with radiation therapy. a lateral photon field can be used to treat this kind of tumor, which has a side‑effect on normal tissue in the opposite side of the oral cavity. in this study the dosimetric effect of the various shields in oral cavity is evaluated. in this study, a special phantom s...

background: the activity and toxicity of etoposide in women with recurrent ovarian cancer was evaluated in a case series of women with recurrent ovarian cancer who had measurable disease, methods: all patients had plior platinum-based chemotherapy and developed progressive disease, etoposide was given as 50mg/day for 21 days every 4 weeks until progression of disease or prohibitive toxicity, be...

background: oral squamous cell carcinoma (oscc) is one of the most common malignant tumors. its incidence is rated as one among the highest in the world and the use of tobacco in various forms is increasingly associated with the cause of oscc. in oral cancer the study of tumor markers have been limited and several tumor makers with clinical promise needs further evaluation. methods: present stu...

cancer of the oral cavity accounts for approximately 3% of all malignancies diagnosed annually in 270,000 patients worldwide. oral cancer is the 12th most common cancer in women and the 6th in men. many oral squamous cell carcinomas develop from potentially malignant disorders (pmds). lack of awareness about the signs and symptoms of oral pmds in the general population and even healthcare provi...