AIM A study was designed to investigate whether measurements of the optic nerve diameter (OND) and cross sectional area (ONCSA), as measured by B-scan ultrasonography, are altered in glaucoma. The reproducibility and test-retest variability of echographic estimates of retrobulbar optic nerve dimensions was also tested. METHODS One eye of 49 glaucoma patients and 90 control subjects underwent ...

OBJECTIVES The true optic nerve sheath diameter cutoff value for detecting elevated intracranial pressure is variable. The variability may stem from the technique used to acquire sonographic measurements of the optic nerve sheath diameter as well as sonographic artifacts inherent to the technique. The purpose of this study was to compare the traditional visual axis technique to an infraorbital ...

PURPOSE To determine whether tumor size correlates with histopathological involvement and hence evaluate the rationality of conservative treatment for retinoblastoma. METHODS We retrospectively studied 221 patients (221 eyes) treated for retinoblastoma with enucleation in the Zhongshan Ophthalmic Center of Sun Yat-sen University, China, from October 1995 to December 2004. Histopathological da...

OBJECTIVE The optic nerve is part of the central nervous system, and a rise in intracranial pressure (ICP) can directly affect the perioptic nerve space, leading to an increase in nerve diameter. Transorbital sonography is a safe and easy-to-perform method to measure optic nerve diameter for rapid diagnosis of increased ICP. METHODS The optic nerve diameter was measured in 3 individual occasi...

BACKGROUND Measurement of optic nerve sheath diameter (ONSD) is a fast and non-invasive method in detecting elevated intracranial pressure. However, the reported normal range of ONSD was inconsistent. The objective of the study was to determine the normal range of ONSD in healthy Chinese adults. METHODS Eyeball transverse diameter (ETD), optic nerve diameter (OND), and ONSD were measured by u...

PURPOSE To investigate optic nerve degeneration associated with CLN3 deficiency in a murine model of juvenile neuronal ceroid lipofuscinosis (Batten disease). METHODS Using light and electron microscopy, the density and diameter of axons and the thickness of myelin in optic nerve were compared between age-matched cln3 knock-out (cln3-/-) and wild-type (129ev/TAC) mice. Western blot analysis w...

Introduction Preeclampsia / eclampsia is a potentially serious disease associated with maternal complications, including neurological. In patients with increased intracranial pressure, the diameter of the optic nerve sheath increases because of its close association with the flow of cerebrospinal fluid. Her measurements using ultrasound transorbital have shown correlation with increased intracr...

PURPOSE To evaluate orbital blood flow velocities and optic nerve diameter with Doppler and gray-scale sonography in patients with acute unilateral optic neuritis (ON). METHODS Orbital Doppler and gray-scale sonography was performed in 46 eyes of 23 patients aged 19- to 47-years with acute unilateral ON. ON was diagnosed by an ophthalmologist on the basis of clinical presentation, presence of...

BACKGROUND There is not any data available about the effect of high bar pressure condition on intracranial pressure. In this study, the effect of diving on the optic nerve and sheath diameters as non-invasive markers of intracranial pressure has been investigated. METHODS Twenty professional male divers from twenty one volunteers were chosen for this cross-sectional study. Only one person who...