Background: Opioid use disorder is a major concern to public health, and opioid maintenance treatment onmethadone or buprenorphine is a widely used approach. On the other hand, in recent years, there has beenmore regards for the use of opium tincture for detoxification and maintenance treatment of opioiddependence in certain parts...

BACKGROUND The knowledge and acceptance of the concept of brain death among future health professionals is essential. The objective of this study was to analyze the knowledge of the concept of brain death among nursing students at the Medical University of Warsaw and determine the factors that affect it. METHODS Academic year 2011-2012, nursing students of the University of Poland. Sampling p...

OBJECTIVE The purpose of this study was to test the hypothesis that treatment of neonatal opiate withdrawal (NOW) in the term infant with diluted tincture of opium (DTO) and phenobarbital was superior to treatment with DTO alone. STUDY DESIGN This was a partially randomized, controlled trial in which 20 term infants exposed to methadone and/or heroin in utero were studied. The severity of NOW...

In this work, a convenient method for determination of relative UV response factors (RRFs) of morphine, codeine, thebaine, oripavine, noscapine and papaverine by high performance liquid chromatography (HPLC) equipped with a diode array detector (DAD) was presented. Pholcodine was selected as the reference compound for calculating the relative response factors of the alkaloids. The separation of...

ted into hospital late on the evening of the 4th instant, complaining of slight pain in the abdominal region. Previous history.?In September 1867 was in hospital 7 days "with intermittent fever, and in October of the same year, again suffered from intermittent fever for 8 days. Never had any other disease. Present condition.?Bowels not moved for 3 or 4 days; pulse 83; respiration rather hurried...

lie was .completely unable to make water. A hip-bath and a good dose of laudanum having been first tried without advantage, several attempts Were made to pass a catheter into the bladder, but all without success. Some other means of relieving him then forced itself on my attention. At the time, especially as he was a young man with a small prostate, I would have preferred the puncture bv the re...

opportunity. I went to Hong-Kong and was accidentally asked to see a brother officer's patient, a soldier, dying of dysentery. He was an invalid. I prescribed ipecacuanha one dose. Ife had so good a night's rest that my friend requested I would take charge of the case. He got, comparatively speaking, well and went to England ; but this man was not treated by lurgc doses, nor have I ever found l...

UNLABELLED Treating pain is one of the most difficult challenges in medicine and a key facet of disease management. The isolation of morphine by Friedrich Sertürner in 1804 added an essential pharmacological tool in the treatment of pain and spawned the discovery of a new class of drugs known collectively as opioid analgesics. Revered for their potent pain-relieving effects, even Morpheus the g...

Koch (1886) studied the effect of cholera vibrios on guinea-pigs by feeding the animals with big doses of the organisms and then paralysing the gut by intraperitoneal injection of 1 c.cm. of tincture of opium so as to delay evacuation. Out of 35 animals, 30 died showing weakness of the hind limbs and collapse. The small intestine was deeply injected and filled with a;flocculent colourless fluid...