نتایج جستجو برای: opalin

تعداد نتایج: 20  

2013
Wanxiang Jiang Wanchun Yang Weiwei Yang Junyan Zhang Dejiang Pang Lingxue Gan Liping Luo Yingjun Fan Yanhui Liu Mina Chen

Oligodendrocytes ensheath axons to form compact insulating multilamellar structures known as myelin. Tmem10 is a novel type I transmembrane glycoprotein that is highly expressed in oligodendrocytes and whose biological function remains largely unknown. Furthermore, the expression pattern of Tmem10 remains a matter of some controversy. Given the inconsistency of its expression pattern and the la...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2012
Oliver Tress Marta Maglione Dennis May Tatjyana Pivneva Nadine Richter Julia Seyfarth Sonja Binder Armin Zlomuzica Gerald Seifert Martin Theis Ekrem Dere Helmut Kettenmann Klaus Willecke

In this study, we have investigated the contribution of oligodendrocytic connexin47 (Cx47) and astrocytic Cx30 to panglial gap junctional networks as well as myelin maintenance and function by deletion of both connexin coding DNAs in mice. Biocytin injections revealed complete disruption of oligodendrocyte-to-astrocyte coupling in the white matter of 10- to 15-d-old Cx30/Cx47 double-deficient m...

2014
Véronique Dorval Wim Mandemakers Francis Jolivette Laetitia Coudert Rachid Mazroui Bart De Strooper Sébastien S. Hébert

Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most frequent cause of genetic Parkinson's disease (PD). The biological function of LRRK2 and how mutations lead to disease remain poorly defined. It has been proposed that LRRK2 could function in gene transcription regulation; however, this issue remains controversial. Here, we investigated in parallel gene and microRNA (miRNA) transcri...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2010
Richa B Tripathi Leanne E Rivers Kaylene M Young Francoise Jamen William D Richardson

The adult mammalian brain and spinal cord contain glial precursors that express platelet-derived growth factor receptor α subunit (PDGFRA) and the NG2 proteoglycan. These "NG2 cells" descend from oligodendrocyte precursors in the perinatal CNS and continue to generate myelinating oligodendrocytes in the gray and white matter of the postnatal brain. It has been proposed that NG2 cells can also g...

Journal: :Türkiye jeoloji bülteni 2022

İnlice yüksek sülfidasyon epitermal altın yatağı, Erenlerdağ-Alacadağ Volkanik Kompleksi (EAVK) içerisinde ve Konya ilinin yaklaşık 40 km güneybatısında yer almaktadır. Çalışma alanında stratigrafik konumlarına göre alttan üste doğru andezit, blok kül akıntısı, bazaltik andezit lav akıntısı olmak üzere dört birime ayrılan volkanik volkano-sedimanter kayaçlar, yamaç molozu alüvyonlar tarafından ...

2016
Ioanna Sevastou Gareth Pryce David Baker David L Selwood

Multiple sclerosis (MS) is a debilitating immune-mediated neurological disorder affecting young adults. MS is primarily relapsing-remitting, but neurodegeneration and disability accumulate from disease onset. The most commonly used mouse MS models exhibit a monophasic immune response with fast accumulation of neurological damage that does not allow the study of progressive neurodegeneration. Th...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید