BACKGROUND Healthcare professionals working in the community do not always prescribe oral nutritional supplements (ONS) according to best practice guidelines for the management of malnutrition. The present study aimed to determine the impact of a community dietetics intervention on ONS prescribing practices and expenditure 1 year later. METHODS The intervention involved general practitioners ...

Two phosphate modifications were introduced into the DNA backbone using Staudinger reaction between 3’,5’-dinucleoside ?-cyanoethyl phosphite triester formed during synthesis and sulfonyl azides, 4-(azidosulfonyl)- N,N,N -trimethylbutan-1-aminium iodide (N+ azide) or p -toluenesulfonyl (tosyl Ts) azide, to provide either a zwitterionic phosphoramidate with N+ modification negatively charged for...

OBJECTIVES To assess the effect of inpatient oral nutritional supplement (ONS) use on length of stay, episode cost, and 30-day readmission probability. STUDY DESIGN Eleven-year retrospective study (2000 to 2010). METHODS Analyses were conducted using the Premier Perspectives Database, which contained information on 44.0 million adult inpatient episodes. Using a matched sample of ONS and non...

E76 E nvironmental scanning is a systematic effort to obtain information about the world that will affect an organization. Scanning is important in managing change and avoiding costly mistakes. The Oncology Nursing Society (ONS) conducts an environmental scan at three-year intervals, consistent with its strategic planning cycle. This environmental scan builds on previous work by incorporating a...

Targeted mutagenesis directed by oligonucleotides (ONs) is a promising method for manipulating the genome in higher eukaryotes. In this study, we have compared gene editing by different ONs on two new target sequences, the eBFP and the rd1 mutant photoreceptor betaPDE cDNAs, which were integrated as single copy transgenes at the same genomic site in 293T cells. Interestingly, antisense ONs were...

In this paper, we introduce a notion of generalized states from an EQ-algebra E1 to another EQ-algebra E2, which is a generalization of internal states (or state operators) on an EQ-algebra E. Also we give a type of special generalized state from an EQ-algebra E1 to E1, called generalized internal states (or GI-state). Then we give some examples and basic properties of generalized (internal) st...

In This Issue In This Issue Nuclear proteins get around rotein trafficking between the cytoplasm and the nucleus has been studied extensively; but how do proteins move from one site to another within the nu-cleus? On page 615, Leung and Lamond focus on the intranuclear trafficking of the RNA-binding protein NHPX, and describe an elegant series of experiments that demonstrates the existence of m...

Following optic nerve section (ONS) in goldfish, the right eye was repeatedly injected with tetrodotoxin (TTX) and the left eye with Ringer solution. At various survival periods after ONS, horseradish peroxidase (HRP) was applied to small groups of axons in dorsal or ventral retina in both eyes. Counts of labeled regenerating retinal axons show that 43 +/- 4.6% of regenerating axons course thro...