The oral glucose minimal model (OMM) measures insulin sensitivity (S(I)) and the glucose rate of appearance (R(a)) of ingested glucose in the presence of physiological changes of insulin and glucose concentrations. However, S(I) of OMM measures the overall effect of insulin on glucose utilization and glucose production. In this study we show that, by adding a tracer to the oral dose, e.g., of a...

Background: To investigate the relationship between clinical and histopathological characteristics and overall survival of patients with oral mucosal melanoma (OMM) without distal metastasis in order to provide predictive prognostic information of OMM. Methods: Ki67 expression was assessed by immunohistochemistry in 123 patients with OMM without distant metastases. The associations between Ki67...

Recent studies have revealed a role for the ubiquitin/proteasome system in the regulation and turnover of outer mitochondrial membrane (OMM)-associated proteins. Although several molecular components required for this process have been identified, the mechanism of proteasome-dependent degradation of OMM-associated proteins is currently unclear. We show that an AAA-ATPase, p97, is required for t...

Voltage dependent anion channels (VDACs) are pore-forming proteins (approximately 30 kDa) associated with mitochondria, the membrane-bound organelles found in almost all eukaryotes. Commonly referred to as the “power-generators of cells”, mitochondria are composed of binary membranes, an outer membrane (OMM; outer mitochondrial membrane) and an inner membrane (IMM; inner mitochondrial membrane)...

In this paper, a Prototype design of electronic coupons ecosystem using NFC (Near Field Communication) in smart phones with OMM (Object Memory Model) is presented. The goal of OMM is to support the life cycle of NFC-based Electronic Coupon ecosystem for profile and usage, from E-Coupon push service and to E-Coupon clearance, using smart phone based on NFC devices. We propose the E-Coupon with O...

Mitochondria perform multiple functions critical to the maintenance of cellular homoeostasis and their dysfunction leads to disease. Several lines of evidence suggest the presence of a MAD (mitochondria-associated degradation) pathway that regulates mitochondrial protein quality control. Internal mitochondrial proteins may be retrotranslocated to the OMM (outer mitochondrial membrane), multiple...

BACKGROUND Oral malignant melanoma (OMM) is an aggressive tumor with very low survival rate and easy to metastasize. Pleural metastatic melanoma via primary OMM is rare. CASE PRESENTATION In this report, we presented a case of metastatic malignant melanoma of the pleura originated from OMM. A 54-year-old man without primary skin lesion was diagnosed multiple nodular shadows, pleural invasion,...

Focused attention (FAM) and open monitoring (OMM) meditation types establish distinct metacontrol states that have immediate effects on how attention allocation strategies are utilised in subsequent, unrelated tasks. Because attention allocation is a central factor in sequential action, the present experiment investigated whether a single-session of FAM and OMM enhanced subsequent sequence perf...

Focused attention (FAM) and open monitoring (OMM) meditation types establish distinct metacontrol states that have immediate effects on how attention allocation strategies are utilized in subsequent, unrelated tasks. Because attention allocation is a central factor in sequential action, the present experiment investigated whether a single-session of FAM and OMM enhanced subsequent sequence perf...

CONTEXT The use of cranial osteopathic manipulative medicine (OMM) to alter cerebral tissue oxygen saturation could play a role in the maintenance of cerebral homeostasis. OBJECTIVE To examine the effects of cranial OMM on cerebral tissue oxygen saturation (S(CT)O(2)) and cardiac autonomic function in healthy adults. METHODS Cranial OMM augmentation and suppression techniques and sham thera...