Abnormal lower limb swelling is variously referred to as chronic oedema, lymphovenous oedema, lymphoedema or lipoedema (Todd, 2012). Generally, oedema is defined as an ‘accumulation of fluid in the intercellular tissue that results from an increased volume of fluid’ (Trayes et al, 2013). Chronic oedema includes oedema which develops as a result of venous disease, dependency oedema and lymphoven...

A series of five-membered heterocyclic rings were synthesized by the reaction between benzoyl chloride and various chlolro-nitro-benzoyl chlorides and semi carbazide to form (C1-C7) compounds and was tested for their anti-inflammatory activity determined by rat-paw-oedema method. All the synthesis compounds have been characterized by 1HNMR, IR and Mass spectral data. The compounds were purified...

Macular oedema typically results from blood-retinal barrier disruption. It has recently been reported that patients with multiple sclerosis treated with FTY-720 (fingolimod) may exhibit macular oedema. Multiple sclerosis is not otherwise thought to be associated with macular oedema except in the context of comorbid clinical uveitis. Despite a lack of myelin, the retina is a site of inflammation...

Although overexpression of vascular endothelial growth factor (VEGF) 165 in the lung causes pulmonary oedema, its role in human acute lung injury (ALI) is unclear. VEGF levels are reported to be lower in bronchoalveolar lavage from ALI patients compared with normals, but these studies did not include a comparably ill control group with noninflammatory pulmonary oedema. The current authors hypot...

a series of five-membered heterocyclic rings were synthesized by the reaction between benzoyl chloride and various chlolro-nitro-benzoyl chlorides and semi carbazide to form (c1-c7) compounds and was tested for their anti-inflammatory activity determined by rat-paw-oedema method. all the synthesis compounds have been characterized by 1hnmr, ir and mass spectral data. the compounds were purified...

Extracellular accumulation of fluid resulting in oedema is well tolerated in most tissues of the body, but in the retina, it results in dysfunction of retinal neurons. Collection of fluid in the macula is called macular oedema and when the fovea is involved, it results in decreased visual acuity. Macular oedema occurs in a wide variety of ocular diseases and is one of the most prevalent causes ...

Background Ischemic cell death is characterised by cellular oedema. Reperfusion may be expected to increase myocardial oedema via hyperaemia and osmotic changes. Cardiovascular magnetic resonance (CMR) can be used to detect oedema using T2 weighted imaging, but this technique does not allow the study of possible changes in oedema with reperfusion. The purpose of this study was to examine the de...

INTRODUCTION Although laser photocoagulation is the primary treatment for diabetic macular oedema, treatment of eyes with diffuse macular oedema has been disappointing. Intravitreal injection of steroids is being investigated for the treatment of diabetic macular oedema. Preliminary results indicate that steroid injections do improve macular oedema, but it is not clear if they improve visual ac...

Regional cerebral blood flow (rCBF) and oedema following profound temporary ischaemia were studied in the gerbil. Ninety-four per cent of animals died within 24 hours of reperfusion; 50% by 4 hours. Regional differences in oedema (specific gravity method), Evans blue (EB) staining and rCBF (hydrogen clearance technique) occurred. Oedema developed during arterial occlusion, being inversely propo...

BACKGROUND Several previous studies have shown that circulating levels of tumor necrosis factor-alpha (TNF) are elevated in patients with advanced congestive heart failure. However, the relationship between circulating levels of TNF and severity of peripheral oedema in these patients has not been previously evaluated. AIMS To investigate the relationship between circulating levels of TNF, and...