An ocular manifestation of a systemic disease is an ocular condition that directly or indirectly results from a pathologic process from another part of the body. Ocular manifestations can occur in various systemic diseases in pediatrics. However, ocular manifestations are difficult to recognize especially in pediatric diseases because most clinicians ignore ocular involvement of systemic diseas...

the aim of this study was to determine the prevalence and type of ophthalmic diseases among horse populations in the suburbian riding clubs of tehran. ophthalmologic examinations were performed in 901 horses and ocular lesions were diagnosed in 40 (4.4%) animals. in the 54 eyes of these horses that had ocular defects, 103 ocular abnormalities were detected. of those horses affected, 65% showed ...

The Ocular Disease Ontology (ODO) is an ontology designed to represent ocular diseases for both clinical and research purposes. This constitutes an effort to build an ontology that represents, to the fullest possible extent, ocular diseases. ODO makes use of the following: Cell Ontology (CL), Ontology for General Medical Science (OGMS), Neuronal CL, Gene Ontology (GO), Uberanatomy Ontology (UBE...

Epigenetics pertains to heritable alterations in gene expression that do not involve modification of the underlying genomic DNA sequence. Historically, the study of epigenetic mechanisms has focused on DNA methylation and histone modifications, but the concept of epigenetics has been more recently extended to include microRNAs as well. Epigenetic patterning is modified by environmental exposure...