AIM To report the failure of amniotic membrane transplantation (AMT) for ocular surface reconstruction in patients with severe acute chemical and thermal burns. METHODS Four eyes of three patients who suffered severe chemical (n=3) and thermal (n=1) burns were studied. The aim of AMT was to prevent symblepharon formation, promote conjunctival regeneration, inhibit corneal melting by promoting...

We have read the paper entitled “The Ocular Surface Chemical Burns” by M. Eslani et al. with great interest [1]. We congratulate the authors that they composed a thorough review with precious pearls and would like to make a contribution. In case of a chemical injury, if stromal nerve endings get seriously harmed, sensation and pain could be reduced. This would be in contradiction with the sever...

http://bjo.bmj.com/content/95/2/159.full.html Updated information and services can be found at: These include: References http://bjo.bmj.com/content/95/2/159.full.html#ref-list-1 This article cites 25 articles, 6 of which can be accessed free at: service Email alerting box at the top right corner of the online article. Receive free email alerts when new articles cite this article. Sign up in th...

Ocular chemical burns are produced by irritants, acids or alkalis. Their severity depends on the type of causative substance, its concentration, physical form, duration contact, ocular surface area affected and delay in medical attention. Severe cases can be difficult to manage posing a challenge for general practitioners ophthalmology specialists. This review aims describe protocol action thei...

PURPOSE To evaluate the role of macrophage migration inhibitory factor (MIF) in the wound healing process following severe chemical burns to the ocular surface. METHODS Chemical burning of the ocular surface was induced in mice (C57BL/6) via the application of 0.1 M NaOH. Macrophage migration inhibitory factor (MIF), tumor necrosis factor-α (TNF-α), and interleukin-1β (IL-1β) mRNA expression ...

Background: Ocular chemical burns induce devastating and permanent damage to the ocular surface. Rapid intervention is required for maximal visual rehabilitation. Amniotic membrane transplantation (AMT) may save the ocular surface, however it introduces a potentially unnecessary surgical trauma in such compromised eyes. Amniotic membrane extracts (AME) could be a practical substitute of AMT in ...

OBJECTIVE To evaluate outcomes of limbal allograft transplantation from living-related donors to treat partial limbal deficiency secondary to ocular chemical burns. METHODS Retrospective noncomparative case series comprising 17 patients (17 eyes) with partial limbal deficiency (≤50%) secondary to ocular alkali burns (11 eyes) or acid burns (6 eyes). Recipient eyes were treated by removing the...

Background: The determination of common diseases in a region is a medical and health priority of that region. Ocular emergencies can cause permanent vision loss if they are not recognized and treated promptly.  Preserve vision of patients, We arranged this study  in Moradi hospital (Kerman, Iran), to estimate our regional situation. Materials and Methods: In this cross-sectional stud...

Ocular chemical injuries accounts for 11.5% to 22.1% of ocular injuries. burns are an ophthalmic emergency and requires immediate treatment. We report a series three cases injury secondary accidental exposure red balm used as local application headache. In our menthol, cajuput oil capsaicin might have contributed nerve damage. Nerve damage lead delayed epithelial healing. All patients improved ...

BACKGROUND In our earlier genome-wide association study on Stevens-Johnson Syndrome (SJS) and its severe variant, toxic epidermal necrolysis (TEN), we found that in Japanese patients with these severe ocular surface complications there was an association with prostaglandin E receptor 3 (EP3) gene (PTGER3) polymorphisms. We also reported that EP3 is dominantly expressed in the ocular surface-, e...