The aim of the present study was to evaluate serum leptin levels to demonstrate whether or not its eventual alterations might have an etiopathogenetic significance in patients with obsessive-compulsive disorder (OCD). Thus, it was planned to examine whether serum leptin levels were affected by pure OCD (OCD-D), pure depression (D) or the comorbidity of OCD and depression (OCD+D). Forty-four pat...

high comorbidity between psychological disorders causes attention to the mechanisms responsible for this comorbidity and common cognitive factors involved in these disorders. these are known as transdiagniostic factors. similarity evidence and high comorbidity between generalized anxiety disorder (gad) and obsessive compulsive disorder (ocd) introduce them as neighboring disorders. the purpose ...

Obsessive compulsive disorder (OCD) is a type of anxiety disorder characterized by recurrent, intrusive, unwanted thoughts. Research indicates a genetic predisposition for OCD. Many people with OCD have one or more family members who also have it or who may have other anxiety disorders influenced by the brain's serotonin levels, such as panic disorder. Although OCD is a chronic and oftentimes d...

BACKGROUND The purpose of this study was to assess clinical characteristics, including co-morbid personality disorders in patients with both anorexia nervosa (AN) and obsessive-compulsive disorder (OCD) in comparison with age- and sex-matched patients with OCD. METHODS Fifty-three female patients with AN were divided into two groups based on the presence or absence of a current diagnosis of O...

BACKGROUND Research on the utility of structured interviews in assessing OCD is scarce, and even more so, in its use for OCD in African Americans. The purpose of this study was to examine the utility of the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I) in detecting OCD in African Americans when used by well-trained, culturally competent clinicians. METHODS Seventy-four Af...

This study investigated the neurocognitive correlates of childhood OCD and TS, which are purported to share frontal-striatal dysfunction. Neurocognitive measures tapping frontal-striatal functions such as executive, attention/memory, and visuomotor abilities were administered to three groups of participants, OCD without comorbid TS (OCD), TS without comorbid OCD (TS), and normal controls. Resul...

obsessive compulsive disorder (ocd) is a type of anxiety disorder characterized by recurrent, intrusive, unwanted thoughts. research indicates a genetic predisposition for ocd. many people with ocd have one or more family members who also have it or who may have other anxiety disorders influenced by the brain's serotonin levels, such as panic disorder. although ocd is a chronic and oftenti...

INTRODUCTION Major depressive disorder (MDD) is the most frequent comorbid psychiatric condition associated with obsessive-compulsive disorder (OCD). This study aimed to evaluate the prevalence of current depression in OCD, differences in socio-demographic and clinical characteristics, and obsessive-compulsive symptoms between OCD patients with and without depression. Additionally, factors asso...

Patients with obsessive-compulsive disorder (OCD) have increased rates of neurological soft signs (NSS) when compared to healthy controls. However, previous findings have been confounded by the presence of co-morbidity with disorders themselves associated with increased NSS, such as schizophrenia. Moreover, it remains unclear whether NSS in OCD reflect a vulnerability to this disorder. This stu...

OBJECTIVE The error-related negativity (ERN) is a negative deflection in the event-related potential after an incorrect response, which is often increased in patients with obsessive-compulsive disorder (OCD). However, the relation of the ERN to comorbid tic disorders has not been examined in patients with OCD. This study compared ERN amplitudes in patients with tic-related OCD, patients with no...