although primary chronic hypertension (htn) is increasingly common in adolescence, secondary forms of htn are more common among children. primary htn is associated with being overweight and/or a positive family history of htn. carotid intima-media thickness, a known risk factor for atherosclerosis is frequent in both adults and children with htn and other associated cardiovascular (cv) risk fac...

BACKGROUND An inverse relationship between body mass index (BMI) and circulating levels of N-terminal proB-type natriuretic peptide (NT-proBNP) has been demonstrated in subjects with and without heart failure. Obesity also has been linked with increased incidence of atrial fibrillation (AF), but its influence on NT-proBNP concentrations in AF patients remains unclear. This study aimed to invest...

Aim. To investigate the obesity paradox by studying impact of overweight and abdominal on prognosis in chronic heart failure (CHF) patients with moderately reduced or preserved left ventricular ejection fraction (LVEF) five-year follow-up results. Materials methods. A prospective, open, parallel-group study included 314 CHF LVEF, average age was 65.3 ± 11.2 years. Group 1 – 66 normal weight; 2 ...

BACKGROUND Obesity has been associated with increased risk of heart failure, but whether overweight also increases risk is unclear. It is also unclear whether abdominal adiposity is more strongly associated with heart failure risk than general adiposity. We conducted a systematic review and meta-analysis of prospective studies to clarify the strength and shape of the dose-response relationship ...

BACKGROUND Extreme obesity is recognized to be a risk factor for heart failure. It is unclear whether overweight and lesser degrees of obesity also pose a risk. METHODS We investigated the relation between the body-mass index (the weight in kilograms divided by the square of the height in meters) and the incidence of heart failure among 5881 participants in the Framingham Heart Study (mean ag...

Obesity and heart failure are two of the leading causes of morbidity and mortality in the world. The relationship between obesity and cardiovascular diseases is complex and not fully understood. While the risk of developing heart failure has been shown to be higher in patients who are obese, there is a survival advantage for obese and overweight patients compared with normal weight or low weigh...

OF DISSERTATION Heather Payne-Emerson