1. A precocious development of UDP-glucuronosyltransferase activity (EC 2.4.1.17) towards o-aminophenol is demonstrated in 15-17 day foetal rat liver in utero after dexamethasone administration to the mother. 2. This stimulation of liver transferase activity in utero is directly proportional to the dose of dexamethasone infected. 3. Precocious development of transferase activity in utero can al...

(31 %), m-nitrophenol (9%), p-nitrophenol (9%), m-aminophenol (4%), o-aminophenol (3 %), 4nitrocatechol (0.7 %), aniline (033%) and o-nitrophenol (0.1%). Two new metabolites, nitroquinol (0.1%) and p-nitrophenylmercapturic acid (0.3%), were found in the urine. 4. The denitration products, phenol, catechol, L-phenylmercapturic acid, and trans-tran8-muconic acid, did not occur in the urine. 5. Ni...

A novel magnetite nanoparticle-based heterogeneous acidic catalyst [Fe3O4@SiO2@Am-PPC-SO3H] [HSO4] was successfully prepared and characterized by SEM, EDX, TGA, VSM and FT-IR techniques. The magnetically retrievable and sustainable catalyst was investigated in the reaction of aldehyde and o-aminophenol for the synthesis of benzoxazoles. The...

Two-dimensional x-ray correlation spectra (2DXCS) obtained by varying two delay periods in a time-resolved coherent all-x-ray four-wave-mixing measurement are simulated for the N 1s and O 1s transitions of aminophenol. The necessary valence and core-excited states are calculated using singly and doubly substituted Kohn-Sham determinants within the equivalent-core approximation. Sum-over-states ...

Maleic anhydride was reacted with p-aminophenol and p-toluidine in the presence of di-phosphorus pentoxide (P₂O₅) as a catalyst to produce two compounds: N-(4-hydroxy-phenyl)maleimide (I) and N-(4-methylphenyl)maleimide (II). The new azo compounds I(a-c) and II(a-c) were prepared by the reaction of I and II with three different aromatic amines, namely aniline, p-aminophenol and p-toluidine. The...

The quinimine form of p-aminophenol inhibits the oxygen uptake of tissue suspensions and in very small concentrations inhibits specifically the oxidation of hypoxanthine and xanthine to uric acid by the xanthine oxidase of liver (1). Closely related compounds such as o-aminophenol, p-phenylenediamine, and quinone, although they inhibit to different degrees the oxygen uptake of tissues, have no ...

Oor N-arylated aminophenol products constitute a common structural motif in various potentially useful therapeutic agents and/or drug candidates. We have developed a complementary set of Cuand Pd-based catalyst systems for the selective Oand N-arylation of unprotected aminophenols using aryl halides. Selective O-arylation of 3and 4-aminophenols is achieved with copper-catalyzed methods employin...

Oor N-arylated aminophenol products constitute a common structural motif in various potentially useful therapeutic agents and/or drug candidates. We have developed a complementary set of Cuand Pd-based catalyst systems for the selective Oand N-arylation of unprotected aminophenols using aryl halides. Selective O-arylation of 3and 4-aminophenols is achieved with copper-catalyzed methods employin...