Tension stiffening is a characteristic behavior of reinforced concrete (RC) beams which is directly affected by the bond-slip property of steel bar and concrete interfaces. A beam strengthened with a near-surface mounted (NSM) technique would be even more affected by tension stiffening, as the NSM reinforcement also possess a bond-slip property. Yet assessing how much the tension stiffening of ...

FGSS118 Reproduction in the 21st Century This course will cover basic human reproductive biology, new and future reproductive and contraceptive technologies, and the ethics raised by reproductive issues. Offering: Crosslisting Grading: A-F Credits: 1.00 Gen Ed Area: NSM-BIOL, NSM-BIOL, NSM-BIOL, NSM-BIOL, NSM-BIOL Identical With: BIOL118, PHIL118, SISP118, BIOL118, PHIL118, BIOL118, PHIL118, BI...

The M genome segment of Bunyamwera virus (BUNV)-the prototype of both the Bunyaviridae family and the Orthobunyavirus genus-encodes the glycoprotein precursor (GPC) that is proteolytically cleaved to yield two viral structural glycoproteins, Gn and Gc, and a nonstructural protein, NSm. The cleavage mechanism of orthobunyavirus GPCs and the host proteases involved have not been clarified. In thi...

OBJECTIVE To evaluate the oncologic safety of nipple-sparing mastectomy (NSM) for breast cancer patients based on current literature. DATA SOURCES A comprehensive literature search of Medline, Embase databases was conducted for studies published through March 2014. STUDY SELECTION Our search criteria included English-language studies that focused on NSM at nipple-areola complex (NAC) involv...

The movement protein NSm of Tomato spotted wilt tospovirus (TSWV) plays pivotal roles in viral intercellular trafficking. Recently, the TSWV NSm was also identified as an avirulence (Avr) determinant during the Sw-5b-mediated hypersensitive response (HR). However, whether the cell-to-cell movement of NSm is coupled to its function in HR induction remains obscure. Here, we showed that the NSm mu...

Nipple-sparing mastectomy (NSM) is the latest advancement in the treatment of breast cancer, which permits complete preservation of the nipple-areola complex (NAC). Recent studies suggest similar recurrence rates with NSM compared with traditional mastectomy techniques.1–6 Moreover, NSM has been demonstrated in multiple studies to be a safe and effective procedure from a reconstructive perspect...

Specification of the non-skeletogenic mesoderm (NSM) in sea urchin embryos depends on Delta signaling. Signal reception leads to expression of regulatory genes that later contribute to the aboral NSM regulatory state. In oral NSM, this is replaced by a distinct oral regulatory state in consequence of Nodal signaling. Through regulome wide analysis we identify the homeobox gene not as an immedia...

BACKGROUND Rift Valley fever virus is an arthropod-borne human and animal pathogen responsible for large outbreaks of acute and febrile illness throughout Africa and the Arabian Peninsula. Reverse genetics technology has been used to develop deletion mutants of the virus that lack the NSs and/or NSm virulence genes and have been shown to be stable, immunogenic and protective against Rift Valley...

This article proposes a hybrid Particle Swarm Optimization (PSO) based on the Nonlinear Simplex Method (NSM). At late stage of PSO running, when the promising regions of solutions have been located, the algorithm isolates particles which are very close to the extrema and applies the NSM to them to enhance the local exploitation. Experimental results on several benchmark functions demonstrate th...