NADPH oxidases (Nox) represent a family of hetero-oligomeric enzymes whose exclusive biological function is the generation of reactive oxygen species (ROS). Nox-derived ROS are essential modulators of signal transduction pathways that control key physiological activities such as cell growth, proliferation, migration, differentiation, and apoptosis, immune responses, and biochemical pathways. En...

BACKGROUND/AIMS NADPH (nicotinamide adenine dinucleotide phosphate) oxidase (NOX)-mediated oxidative stress plays a key role in promotion of oxidative injury in the cardiovascular system. The aim of this study is to evaluate the status of NOX in endothelial progenitor cells (EPCs) of hyperlipidemic patients and to assess the correlation between NOX activity and the functions EPCs. METHODS A t...

Understanding of how and where NOx formation occurs in industrial boiler is very important for efficient and clean operation of utility boilers. This study aims to numerically simulate the NOx formation using a 3D model furnace of an industrial boiler. The studied boiler is a 160 MW and is gas fired with natural gas. The boiler combustion model is a 3D problem that involves turbulence, combusti...

Aviation NOx emissions promote tropospheric ozone formation, which is linked to climate warming and adverse health effects. Modeling studies have quantified the relative impact of aviation NOx on O3 in large geographic regions. As these studies have applied forward modeling techniques, it has not been possible to attribute O3 formation to individual flights. Here we apply the adjoint of the glo...

Secondary organic aerosol (SOA) formation from photooxidation of α-pinene has been investigated in a photochemical reaction chamber under varied inorganic seed particle acidity levels at moderate relative humidity. The effect of particle acidity on SOA yield and chemical composition was examined under highand low-NOx conditions. The SOA yield (4.2–7.6 %) increased nearly linearly with the incre...

As the regulations of pollutant emission is getting more and more strict, models of pollutant formation, as a part of system level models for control design, are needed. In this thesis NOx (nitrogen oxides) formation is modeled. A method is developed to mix equilibrium and non-equilibrium reaction equations to model NOx formation in combustion processes. This algorithm reduces high-index DAE sy...

In this paper, a new physics-based model for the prediction of NOx emissions produced by diesel engines is presented. The aim of this work is to provide a Mean-Value Model (MVM) adapted for control design and online estimation. The proposed approach is based on the simplification of a zero-dimensional thermodynamic model. Only the main phenomena taking part in NOx formation are kept and they ar...