The neuropeptide pigment-dispersing factor (PDF) is a key transmitter in the circadian clock of Drosophila melanogaster. PDF is necessary for robust activity rhythms and is thought to couple the circadian oscillations of the clock neurons. However, little is known about the action of PDF on individual clock neurons. Here, we combined the period-luciferase reporter system with immunolabeling of ...

An adiabatic, non-radial pulsation study of a 0.563 M⊙DA white dwarf model is presented on the basis of new evolutionary calculations performed in a self-consistent way with the predictions of time dependent element diffusion, nuclear burning and the history of the white dwarf progenitor. Emphasis is placed on the role played by the internal chemical stratification of these new models in the be...

We study a consistent infrared and ultraviolet regularization scheme for the cosmological perturbations. The infrared divergences are cured by assuming that the Universe undergoes a transition between a nonsingular preinflationary, radiation-dominated phase and a slow-roll inflationary evolution. The ultraviolet divergences are eliminated via adiabatic subtraction. A consistent regularization o...

The spatial profiles and the dissipation characteristics of spin-wave quasieigenmodes are investigated in small magnetic Ni81Fe19 ring structures using Brillouin light scattering microscopy. It is found, that the decay constant of a mode decreases with increasing mode frequency. Indications for a contribution of three-magnon processes to the dissipation of higher-order spin-wave quasi-eigenmode...

A new solution for the acoustic field produced by a point source in a wedge-shaped ocean channel with pressure-release boundaries is presented. The solution is in the form of a sum of normal modes, which reduces in the immediate vicinity of the source point to the free-field solution for a point source. The radiation field associated with each mode forms a well-defined beam which diverges as th...

The aim of the present work is to investigate the influence of the Mode-I crack on the plane waves in a linearly fiber-reinforced. A general model of the equations of coupled theory (CD) and Lord-Shulman (LS) theory with one relaxation time are applied to study the influence of reinforcement on the total deformation for an infinite space weakened by a finite linear opening Mode-I crack is solvi...

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BACKGROUND In animals, neuropeptide signaling is an important component of circadian timekeeping. The neuropeptide pigment dispersing factor (PDF) is required for several aspects of circadian activity rhythms in Drosophila. METHODOLOGY/PRINCIPAL FINDINGS Here we investigate the anatomical basis for PDF's various circadian functions by targeted PDF RNA-interference in specific classes of Droso...

Unfortunately, there’s no simple formula for this integral. Instead, tables or numerical approximation routines are used to evaluate it. The normal distribution has a characteristic bell shaped pdf. The center of the bell is at x = μ, and the parameter σ controls the width of the bell. The particular case in which μ = 0, and σ = 1 is referred to as the standard normal random variable. The lette...