Background: Sarcoidosis is a granulomatous multisystem disease of unknown etiology. It has recently been tired to detect Mycobacteria genome in biopsy specimens of patients with sarcoidosis by Polymorphism chain reaction method. Objective: To detect and identify Mycobacteria species in cutaneous lesions of the patients with sarcoidosis by PCR-RFLP. Patients and methods: 20 patients with clinica...

Abstract: The non-tuberculous mycobacteria (NTM) are ‘atypical mycobacteria’ belonging to species other than those classified in the Mycobacterium tuberculosis complex. NTM have been reported cause cross-reactive immune responses that interfere with diagnosis of both livestock and wildlife considered as potential pathogens for animals humans. present study was conducted detection non- tuberculo...

Guidelines have been produced for tuberculosis by the British Thoracic Society (BTS), 2 the American Thoracic Society (ATS), the International Union Against Tuberculosis and Lung Disease, and the World Health Organisation. These, however, deal mainly with Mycobacterium tuberculosis complex infections (M tuberculosis, M africanum, and M bovis). With the exception of the ATS guidelines on non-tub...

BACKGROUND Patients with non-tuberculous mycobacteria are usually started on conventional antituberculous triple therapy once acid fast bacilli are detected, before the exact type of mycobacteria has been identified. The ability to identify the characteristics of patients with tuberculous and non-tuberculous mycobacteria may be helpful in identifying before treatment those patients more likely ...

Tuberculosis (TB) is the commonest cause of infection-related death globally. Disseminated tuberculosis a life-threatening disease which results from hematogenous spread Mycobacterium tuberculosis. Genitourinary (GUTB) usually caused as result mycobacteria during initial infection. The patient's clinical presentation may vary asymptomatic to non-specific symptoms related organ involved and also...

Non-tuberculous Mycobacteria (NTM) are emerging as an important opportunistic pathogen. Since clinical presentation of NTM infection is similar to tuberculosis (TB), patients present suspected TB or drug resistant TB. Presently in the National Tuberculosis Elimination Programme (NTEP ) not being speciated, but there urgent need characterize so that appropriate treatment can be given many specie...

During the last few years a number of reports have appeared in literature regarding isolation of mycobacteria from patients of tuberculosis, which were different in several respects from the well known Mycobacterium tuberculosis hominis or bovis. (Buhler and Pollak, 1953, Tempe and Runyon, 1954. Nassau and Hamilton, 1957, Davis, et al, 1966). These Mycobacteria have been designated as “Anonymou...

There are strong evidences that Mycobacterium tuberculosis survives in a non-replicating state in the absence of oxygen in closed lesions and granuloma in vivo. In addition, M. tuberculosis is acid-resistant, allowing mycobacteria to survive in acidic, inflamed lesions. The ability of M. tuberculosis to resist to acid was recently shown to contribute to the bacillus virulence although the mecha...