OBJECTIVE The goal of the study was to compare conventional mammography (MG) and contrast-enhanced spectral mammography (CESM) in preoperative women. MATERIALS AND METHODS The study was approved by the local Ethics Committee and all participants provided informed consent. The study included 152 consecutive patients with 173 breast lesions diagnosed on MG or CESM. All MG examinations and consu...

BACKGROUND Infiltrating basal cell carcinoma (BCC) has associated features that may be readily identified using dermatoscopy. OBJECTIVE Investigate a stellate dermatoscopy pattern extending from the peripheral margin of infiltrating BCC. METHODS A total of 741 consecutive cases of BCC were assessed retrospectively using non-polarized dermatoscopy. Following histopathologic examination, case...

background: breast cancer is the most common type of malignancy in the female population, rarely is reported by thromboembolic events during the course of the disease. in this case, we present a rare case of breast cancer presenting as deep vein thrombosis of the axillary vein.case presentation: a 40-year- old female was admitted due to pain and swelling of her right arm and forearm of two mont...

JB In general, little is known about the role that the PD-1 pathway plays in the control of NSCLC. Based on some small studies, PD-1 expression on tumor-infiltrating lymphocytes has shown to decrease cytokine production and decrease the T-cell effector function. Increased expression of the ligand PD-L1 on tumor cells has been correlated with an increase in the number of tumor-infiltrating lymph...

Transient Receptor Potential Vanilloid 1 (TRPV1) and Transient Receptor Potential Ankyrin 1 (TRPA1) expressed mainly by primary sensory neurons function as major nociceptive integrators. They are also present on the rat endometrium in an oestrogen-regulated manner. TRPV1 is upregulated in peritoneal and ovarian endometriosis patients, but there is no information about TRPA1 and their pathophysi...

The underlying mechanisms by which tumor cells are resistant to CTL-mediated apoptosis are not clear. Using a human model of B-cell non-Hodgkin's lymphoma (B-cell NHL), we show that intratumoral T(reg) cells inhibit the proliferation and granule production of activated autologous infiltrating CD8(+) T cells. Our results also show that degranulation and subsequent cytotoxic activity of infiltrat...

Background: Breast cancer is the most common type of malignancy in the female population, rarely is reported by thromboembolic events during the course of the disease. In this case, we present a rare case of breast cancer presenting as deep vein thrombosis of the axillary vein.Case Presentation: A 40-year- old female was admitted due to pain and swelling of her right arm and forearm of two mont...