Background: Simultaneous exposure to noise and organic solvents such as styrene is an indispensable part of today’s industries. Numerous studies were done related to ototoxic effects of co-exposure to noise and styrene while some evidences showed the adverse effects of such exposure on other organs. In this study, we aimed to assess the subacute effects of combined exposure to noise and s...

liver injury occurs with many drugs; therefore, a thorough work up is important for establishing the diagnosis. we report a case of trifluoperazine-induced cholestatic jaundice. a 44-year old male with schizoaffective disorder developed an increase in liver enzymes and jaundice after starting treatment with trifluoperazine. workup for other potential etiologies was negative.

purpose: to investigate tear function in acne vulgaris patients who were treated with isotretinoin (accutane). methods: in this prospective clinical study, patients who were scheduled for isotretinoin (accutane) therapy for two months underwent complete eye examination.the best corrected visual acuity measurement, careful slit lamp examination of anterior segment, evaluation of break-up-time an...

hepatic toxicity is the most serious adverse effect of anti tuberculosis drugs. this study was performed to evaluate efficacy of silymarin as a hepatoprotective herbal agent. in a randomized double blind clinical trial 70 new cases of pulmonary tuberculosis were divided into two groups. the intervention group was assigned to receive silymarin and the control group received placebo. tuberculosis...

background the involved neurotransmitter pathways in the postoperative shivering (pos) are poorly understood. recently, 5-hydroxytryptamine 3 (5-ht3) receptor antagonists have been reported to prevent pos. we investigated the effect of ondansetron, a 5-ht3 antagonist that is used to treat postoperative nausea and vomiting, on shivering. objectives this study aimed to compare the efficacy of ond...