The oculomotor nucleus (nIII) contains the motoneurons of medial, inferior, and superior recti (MR, IR, and SR), inferior oblique (IO), and levator palpebrae (LP) muscles. The delineation of motoneuron subgroups for each muscle is well-known in monkey, but not in human. We studied the transmitter inputs to human nIII and the trochlear nucleus (nIV), which innervates the superior oblique muscle ...

Oxidative addition represents a critical elementary step in myriad catalytic transformations. Here, the importance of thoughtful ligand design cannot be overstated. In this work, we report intermolecular activation iodobenzene (PhI) at coordinatively saturated 18-electron [Ni0(diphosphine)2] complex bearing Lewis acidic secondary coordination sphere. Whereas alkyl-substituted diphosphine comple...

Mononuclear metal-dioxygen adducts, such as metal-superoxo and -peroxo species, are generated as key intermediates in the catalytic cycles of dioxygen activation by heme and non-heme metalloenzymes. We have shown recently that the geometric and electronic structure of the Ni-O2 core in [Ni(n-TMC)(O2)]+ (n = 12 and 14) varies depending on the ring size of the supporting TMC ligand. In this study...

Sulfhydryl reagents affected the binding properties of the translocator domain, NIII, of enzyme IImtl in two ways: (i) the affinity for mannitol was reduced, and (ii) the exchange rate of bound and free mannitol was increased. The effect on the affinity was very much reduced after solubilization of enzyme IImtl in the detergent decylPEG. The effects were caused exclusively by reaction of the su...

A new one-dimensional NiII coordination polymer of 1,3,5-tris-(imidazol-1-ylmeth-yl)benzene, namely catena-poly[[aqua-(sulfato-κO)hemi(μ-ethane-1,2-diol-κ2O:O')[μ3-1,3,5-tris-(1H-imidazol-1-ylmeth-yl)benzene-κ3N3,N3',N3'']nickel(II)] ethane-1,2-diol monosolvate monohydrate], {[Ni(SO4)(C18H18N6)(C2H6O2)0.5(H2O)]·C2H6O2·H2O} n , was synthesized and characterized by elemental analysis, IR spectros...

Interest in polynuclear complexes of the 3d metals has been stimulated by the search for new magnetic materials[1, 2] and by demonstration of the occurrence of oligonuclear metal centers in proteins such as urease.[3] Of the relatively small number of reported tetranuclear complexes of S 1 nickel( ) of known structure, the majority have a hemicubaneor TMbutterfly-∫ rather than a squarelike core...

A pentadentate-[N3O2] ligand, H2LNMe2, formed by condensation of diacetyl pyridine and dimethylcarbamoyl hydrazide (i. e. Me2NCONHNH2), is reported to yield mononuclear pentagonal bipyramidal (PBP) metal complexes with CrIII, MnII, FeII, CoII, NiII, that exhibit good solubility in a wide range solvents as compared the classically used H2LR ligands. With CuII, dinuclear were obtained. The potass...

Complexes of several transition metal ions with alpha-oximinoacetoacetyl pyridine-4-phenylthiosemicarbazone (H3OAPT) have been prepared. Attempts were made to elucidate their geometries by elemental analysis, molar conductance, magnetic measurements and by some spectroscopic (IR, ESR and electronic) techniques. All the investigated metal ions form mononuclear complexes except for CuII, which fo...

Cyclic glyoxalcarbohydrazone[(1,2,4,5,8,9,11,12-octaazacyclotetradeca-5,7,12,14tetraene-3,10-dione) = (glyozalcarbzH)2] complexes of Ni II, PdII, CoII, ZnII and CdII of composition M (glyoxalcarbzH)2X2nH2O (M = Ni II, PdII, CoII,ZnII or CdII and X = Cl> , 1/2 SO4 -2 and n = 0,1 or 4) have been isolated by refluxing appropriate metal salts with glyoxal and carbohydrazide in requisite proportion ...