Noise-induced hearing loss (NIHL) is one of the most common sensorineural hearing deficits. Recent studies have demonstrated that the pathogenesis of NIHL is closely related to ischemia-reperfusion injury of cochlea, which is caused by blood flow decrease and free radical production due to excessive noise. This suggests that protecting the cochlea from oxidative stress is an effective therapeut...

INTRODUCTION Currently, there is limited information about the relationship between manganese superoxide dismutase (sod2) c47t polymorphism and susceptibility to noise-induced hearing loss (NIHL). OBJECTIVE The aim of this meta-analysis was to clarify the association between SOD2 C47T polymorphism and NIHL. METHODS A search in PubMed and Web of Science was performed to collect data. All ful...

Although there is no specific treatment for modality of occupational noise-induced hearing loss (NIHL), the best way to manage this problem is the prevention. The fundamental prevention of NIHL is to find the persons who are more susceptible to the noise and to avoid work in the noisy environment prior to or during employment. The purpose of this study is to investigate the actual status of NIH...

Noise induced hearing loss (NIHL), a multifactorial disease involving both genetic and environmental factors, is one of the most important occupational health hazards. Nonetheless, the influence of FOXO3 variants on NIHL risk have not been illuminated. This research was conducted to explore the effects of FOXO3 polymorphisms on individual susceptibility to NIHL. A total of 2689 industrial worke...

Noise is a major occupational and environmental hazard, causing hearing loss, annoyance, sleep disturbance, fatigue, and hypertension. Although the extra-auditory effects of high-level noise exposure have been reported, noise-induced hearing loss (NIHL) has long been recognized as the primary and most direct health effect of excessive noise exposure. The World Health Organization reported that ...

OBJECTIVE The purpose of this paper is to demonstrate the feasibility and utility of developing economic cost models for noise-induced hearing loss (NIHL). First, we outline an economic model of NIHL for a population of US Navy sailors with an "industrial"-type noise exposure. Next, we describe the effect on NIHL-related cost of varying the two central model inputs--the noise-exposure level and...

St udies carried out by Brainstem Evoked Auditory Potentials (BEAP) in Noise-Induced Hearing Loss (NIHL) workers show different results in relation to neuronal involvement, not involving bus drivers as study object. Aim: to use BEAP in a prospective case/control clinical study to check whether or not there is neural auditory pathway involvement in bus drivers with NIHL. Materials and Methods: w...

Noise-induced hearing loss (NIHL) is an important occupational disorder. However, the molecular mechanisms underlying NIHL have not been fully clarified; therefore, the condition lacks effective therapeutic methods. Cyclooxygenase-2 (Cox-2) is an inducible enzyme involved in the synthesis of prostaglandins, and has been implicated in many pathophysiological events, such as oxidative stress and ...

BACKGROUND Tanzania has a young mining history with several operating open pit and underground mines. No prevalence studies of noise-induced hearing loss (NIHL) have been conducted among mine workers to provide an impetus for the development of comprehensive hearing protection programmes. AIMS To determine the prevalence of NIHL and associated factors among miners in a major gold mining compa...

Noise-induced hearing loss (NIHL) is an important occupational hazard that results from an interaction between genetic and environmental factors. Although the environmental risk factors have been studied quite extensively, little is known about the genetic factors. On the basis of multiple studies, it was proposed that oxidative stress plays an important role in the development of NIHL. Here, w...