background: various infectious agents like ebstein barr virus (ebv), htlv-1 and helicobacter pylori have known as etiologic factors in different sub-types of lymphoma. although hepatitis c virus (hcv) has not only been important for its hepatotropism and hepatitis development, but also in recent years its association with some forms of non- hodgkin’s lymphoma (nhl), especially b cell nhl, has r...

OBJECTIVE Recent research has focused on the effects of corticosteroids and non-steroidal anti-inflammatory drugs/agents (NSAIDs) on non-Hodgkin's lymphoma (NHL) risk, with inconclusive results. We conducted meta-analyses of data published to date, to ascertain the over-all association between NHL and corticosteroid use, and between NHL and NSAID use. METHODS Literature searches were performe...

BACKGROUND T-cell lymphomas (T-NHL) generally carry a poor prognosis. High-dose therapy (HDT) and autologous stem cell transplantation (ASCT) are increasingly used to treat younger patients. DESIGN AND METHODS We treated patients <61 years with high-risk aggressive lymphoma with four to six courses of dose-escalated CHOP plus etoposide (MegaCHOEP) necessitating repeated ASCT. Outcomes of pati...

Lymphomas are classified as Hodgkin's and Non-Hodgkin's lymphomas (HL; NHL); NHL being further sub-divided into B, T and Null cell categories on the basis of WHO classification. With a few exceptions worldwide, B-NHL are more common, accounting approximately 80-85% of all cases of NHL compared to T-NHL, which accounts for about 10-15% of all NHL cases. The incidence of NHL has shown a steady in...

BACKGROUND For decades, non-Hodgkin lymphoma (NHL) incidence has been increasing worldwide. NHL risk is strongly increased among HIV-infected people. Our understanding of trends in NHL incidence has been hampered by difficulties in separating HIV-infected NHL cases from general population rates. METHODS NHL incidence data during 1992-2009 were derived from 10 U.S. SEER cancer registries with ...

background: non-hodgkin lymphoma (nhl) includes a wide range of diseases with different clinical and biological features. nhl is usually presented as localized or generalized lymphadenopathy. it has been suggested that the hla class i and ii are associated with susceptibility to nhl. different ethnic groups have been found to have different hla class i and ii alleles which affect nhl. objective...

Allogeneic hematopoietic cell transplantation (alloHCT) used to play a defined role in the treatment of non-Hodgkin lymphoma (NHL). With advent modern targeted molecular therapies and immunotherapies, standards at least for B-cell have undergone significant changes, thereby questioning traditional alloHCT these diseases. This paper attempts describe current place perspectives rapidly evolving l...

background: the clinical presentation of non-hodgkin lymphoma (nhl) varies tremendously depending upon the type of lymphoma and the areas of involvement. nhl can rarely present as an abdominal mass compressing the inferior vena cava. the clinical presentation due to obstruction of inferior vena cava has often been called the inferior vena cava syndrome (ivcs). it can present acutely or chronica...

Non-Hodgkin lymphoma (NHL) consists of a heterogeneous group of tumors. Population-based data on the familial risk for specific histopathologic subtypes have not been established. Such data are useful for clinical counseling and for searching tumor subtypes sharing common genetic pathways. We used the Swedish Family-Cancer Database to calculate standardized incidence ratios (SIRs) for histopath...