This study, a retrospective chart review of 82 consecutive male inpatients, assessed the spectrum and prevalence of neuroleptic malignant syndrome. The prevalence of diagnosed neuroleptic malignant syndrome (2.4%) was greater than that generally reported. Eight additional patients manifested symptoms that abated without cessation of neuroleptic treatment. This suggests that neuroleptic malignan...

A 55-year-old woman with a history of bipolar affective disorder developed hyperpyrexia, rigidity and depressed consciousness (neuroleptic malignant syndrome) after commencing neuroleptic therapy. On regaining consciousness, she was mute and had signs suggesting pancerebellar involvement. Hyperpyrexia, which is a cardinal feature of neuroleptic malignant syndrome, may have caused cerebellar dam...

ajp.psychiatryonline.org neuroleptic malignant syndrome (1, 2). Other investigators have reported typical neuroleptic malignant syndrome features from treatment with atypical antipsychotics (4). Although our patient presented with neck stiffness, no rigidity was found, and no fever was initially noted. Additionally, he did not manifest a number of symptoms associated with neuroleptic malignant ...

A case of prolonged and refractory neuroleptic malignant syndrome was treated successfully with electroconvulsive therapy. Neuroleptic malignant syndrome and its treatment are reviewed.

When fever occurs in a patient treated with a neuroleptic, the diagnosis of a neuroleptic malignant syndrome is difficult to differentiate to that of an infectious event. Among inflammation biomarkers of inflammation, serum procalcitonin levels increase both quickly and specifically during a bacterial infection. We report the first case of a neuroleptic malignant syndrome associated with a sign...

CONTEXT A case of neuroleptic malignant syndrome and acute respiratory distress syndrome is presented and discussed with emphasis on the role of muscle relaxation, creatine kinase, and respiratory function tests. CASE REPORT A 41-year-old man presented right otalgia and peripheral facial paralysis. A computed tomography scan of the skull showed a hyperdense area, 2 cm in diameter, in the path...

Few conditions have attracted such widespread attention among both neurologists and psychiatrists in recent years as the neuroleptic malignant syndrome. First described in 1960 by French clinicians in a study of haloperidoll and subsequently named the "syndrome malin des neuro-leptiques",2 this nomenclature suffered in translation to the neuroleptic malignant syndrome; this term has endured, in...