Brucellosis, which is endemic in Saudi Arabia, can present as a disease with multisystem involvement. Occasionally the organisms invade the central nervous system producing varied neurological manifestations. Often the clinical diagnosis of neurobrucellosis is not straight forward and is obscure. Certain criteria have to be fulfilled for the definitive diagnosis of neurobrucellosis. We report 2...

how to cite this article: akhondian j, ashrafzadeh f, beiraghi toosi m, hashemi n. a rare presentation of neurobrucellosis in a child with recurrent transient ischemic attacks and pseudotumor cerebri (a case report and review of literature). iran j child neurol. 2014 spring; 8(2):65-69.   brucellosis is a multi-system infectious disease that presents with various manifestations and complication...

Brucellosis remains an important health problem in some parts of the world. The disease has virtually disappeared in Western countries but is still endemic in others. In Kuwait, with a population of 1.6 million, a total number of 1168 fresh cases of brucellosis were reported in 1985, an incidence of 68.9/100,000 population. The general presentation of brucellosis remains well recognized and is ...

Neurobrucellosis is uncommon; however, it is an important complication of brucellosis, which could be seen in any stage of the disease. It presents with different kinds of neurology manifestations and diagnosis is mainly made on history, physical examination and laboratory tests. The clinical course of the disease is relatively insidious and the most common pattern of presentation is subacute o...

BACKGROUND This study aimed to analyze the risk factors and treatment efficacy of neurobrucellosis. MATERIAL/METHODS A cross-sectional epidemiologic survey was carried out in 557 patients with brucellosis by specially trained neurologic clinicians. Sixty-six patients with neurobrucellosis were treated with doxycycline, rifampicin, and ceftriaxone sodium as standard medication and evaluated fo...

Neurobrucellosis manifesting as optic neuritis is a rare disease in childhood. We report a case of neurobrucellosis in a 11 year old girl leading to visual impairment and headache. Physical examination revealed mild oedema of right tibiotarsic joint and optic neuritis. Investigations showed CSF pleocytosis and a Brucella serum agglutination titer of 1/640. Complete reversal of the symptoms was ...

Brucellosis is an infectious disease with high incidence in Iran. Neurobrucellosis is a focal complication of brucellosis affecting both central and peripheral nervous system presenting with a varieties of signs and symptoms. The most reported manifestations are meningitis and meningoencephalitis. In this report, we will describe a case of a young woman affected by neurobrucellosis presenting w...

BACKGROUND We describe the neurological involvement in brucellosis and revisited diagnostic criteria for neurobrucellosis. METHODS Patients with laboratory-confirmed brucellosis who were consequently hospitalized were observed prospectively in a brucellosis-endemic region. The neurobrucellosis was diagnosed by any one of the following criteria: (1) symptoms and signs consistent with neurobruc...

conclusion clinical manifestations and csf abnormality of neurobrucellosis is similar to tuberculosis and neurobrucellosis must be kept in mind in approach of patients with acute or chronic lymphocytic meningitis with increased protein and low glucose level in csf and risk factors of brucellosis. results neurological manifestations include meningitis (64.9%), meningoencephalitis (11.6%), crania...

BACKGROUND Neurobrucellosis is a disease consisting of a wide spectrum of complications such as peripheral neuropathy, cranial nerve involvement, ataxia, meningeal irritation, paraplegia, seizures, coma, and even death. The vestibulocochlear nerve seems to be the most commonly affected cranial nerve (10%). We present a patient with neurobrucellosis whose auditory perception and speech intelligi...