We present an overview of the role of neuro-endocrine-immune mechanisms in the pathophysiological responses of patients with rheumatoid arthritis (RA). In patients with RA, proinflammatory cytokines secreted by synovial cells provoke local inflammation in the joints and, simultaneously, initiate a systemic acute phase response. Thus, profound changes of the neuro-endocrine-immune axis could tak...

Intelligent systems for the diagnosis and classification of Endocrine Myopathy (EM) plays very significant role in the medical field. Neuro-fuzzy system is refers to combinations of artificial neural networks and fuzzy logic, in which fuzzy system works like human reasoning and the learning structure of neural networks. The plan of this paper is to present the Neuro-fuzzy system for the classif...

Background. Earlier we showed, by constructing regression models, that plasma nitrogenous metabolites (uric acid, urea, creatinine and bilirubin) are able to influence the state of trait anxiety, autonomic central nervous endocrine systems. In this study same cohort, other methodological approaches were used. Materials Methods. The object observation almost healthy volunteers: 30 females (30÷76...

This volume presents the proceedings of a neuroimmunology meeting that took place at Rockefeller University under the aegis of the Institute for Child Development Research in 1985. It contains eight chapters which review various aspects of the interface between the autonomic nervous system and the endocrine axis with immune function. The book is intended for a multidisciplinary audience and, co...

IN RESPONSE TO NUTRIENT INTAKE, glucagon-like peptide-1 (GLP-1) is secreted from endocrine cells in gastrointestinal mucosa primarily in the distal ileum and colon (3). Numerous actions of GLP-1 have been described, including reduction of blood glucose via several complementary mechanisms and inhibition of gastric emptying. Several recent reviews discuss these actions in some detail (3–7, 10). ...

The prevalence of obesity has reached pandemic dimensions. It is associated with multiple comorbidities and becoming a clinical public health threat. Obesity multifactorial disease complex pathophysiology interplay various systems. A strong exists between the neuro-endocrine system, immune system systemic chronic low-grade inflammation, microbiome dysbiosis that can lead to development obesity,...