introduction: her2/neu, a member of the epidermal growth factor receptor family, has been shown to be over-expressed in some tumors. the purpose of this study was to determine the salivary levels and tissue expression of her2/neu in patients with head and neck squamous cell carcinoma (hnscc) and their correlation with clinicopathologic parameters.   materials and methods: enzyme-linked immunoso...

  Background and Objectives: Adenoid cystic carcinoma (ACC), the most common malignant tumor of submandibular and minor salivary glands, is characterized by a high rate of local recurrence and distant hematogenous metastasis and tendency to invade peripheral nerves. In spite of radiotherapy and surgical treatment, the long-term prognosis is dismal. Today, many studies are being conducted using...

background: wilms' tumor is an emberyonal tumor arising from remnants of immature renal tissue. her2/neu is an onco-protein which mediates cellular proliferation, differentiation and survival. methods: in the current study, we analyzed her2/neu expression in 40 wilms' tumors. the clinico-demographic data of 40 patients with wilms' tumor were retrieved. immunohistochemical staining for her2/neu ...

Objective HER-2/neu gene is overexpressed in diverse human cancers and studies suggest a role of its product – p185 protein – in tumor progression by specifically promoting the invasive capacity of tumor cells. Our aim was to evaluate HER-2/neu content in resectable gastric cancer in this geographical region and assess the relationship between p185 expression and clinicopathologic tumor paramet...