Parathyroid carcinoma is a rare endocrine neoplasm that accounts for <1% of cases primary hyperparathyroidism. The management parathyroid challenge due to the high rate local recurrence tumour. We report case middle-aged north Indian woman who presented with recurrent hyperparathyroidism carcinoma. She palpable hard neck mass and underwent radical dissection six times. At time writing this r...

dear editor-in-chief   pilomatrixoma is a benign tumor of hair follicle first described as calcifying epithelium (1). it accounts for 1% of all the benign skin tumors (2). it is a slow-growing, firm, dermal or subcutaneous neoplasm, usually measuring fewer than 3 cm in diameter. pilomatricomas are considered benign; rarely recur after surgical excision (3). however, cases of pilomatrixoma with ...

Schwannoma is a rare benign neural neoplasm derived from Schwann cells of the peripheral nerve sheath. Schwannoma accounts for 25% to 48% of all neoplasm cases in the head and neck region. Oral Schwannoma is an uncommon soft tissue tumor comprising of 1% of all Schwannomas. Tongue is the most common location for oral schwannoma. Occurrence of gingival schwannoma is very rare and less than 10 ca...

Primary mucinous carcinoma of the skin is a rare sweat-gland neoplasm with a high recurrence rate. We report a new case of a primary recurrent mucinous carcinoma of the face in a 59-year-old man. Histopathologic examination of the neoplasm showed epithelial islands floating in mucoid material compartmentalized by fibrous septa. Cytokeratin 7, protein S100, estrogen and progesterone receptors we...

Solid-pseudopapillary neoplasm of the pancreas (SPPNP) is a primary epithelial neoplasm of the exocrine pancreas with borderline malignant potential. The unusual features included the ‘giant’ size and the absence of metastases/ capsular or vascular invasion despite the large size and predominantly solid nature. At two years following complete excision, she is asymptomatic and the imaging shows ...

Dear Editor-in-Chief   Pilomatrixoma is a benign tumor of hair follicle first described as calcifying epithelium (1). It accounts for 1% of all the benign skin tumors (2). It is a slow-growing, firm, dermal or subcutaneous neoplasm, usually measuring fewer than 3 cm in diameter. Pilomatricomas are considered benign; rarely recur after surgical excisi...

A solid pseudopapillary neoplasm of the pancreas is a rare pancreatic tumor with a low malignant potential. It typically occurs in young women. Solid pseudopapillary neoplasm associated with extra-pancreatic and pancreatic anomalies are occasionally reported. We report a case of an solid pseudopapillary neoplasm with a concomitant variation of the common hepatic artery in a 43-year-old woman. T...

A 69-year-old woman was referred to our hospital after incidental identification of a pancreatic mass during follow-up for diabetes mellitus. Various imaging examinations showed a tumor in the main pancreatic duct, without apparent hypersecretion of mucin. Brush cytologic examination revealed class V disease (adenocarcinoma). Because preoperative examination suggested an intraductal neoplasm wi...

AIMS The macroH2A histone variants are epigenetic marks for inactivated chromatin. In this study, we examined the expression of macroH2A2 in anal neoplasm from anal intraepithelial neoplasia (AIN) to anal squamous cell carcinoma (SCC). METHODS AIN and anal SCC samples were analysed for macroH2A2 expression, HIV and human papilloma virus (HPV). The association of macroH2A2 expression with clin...