abstract malignant spermatic cord tumor is rare. spermatic cord metastasis is less common and the prognosis of these patients is poor. here we report a case of unilateral spermatic cord metastasis from advanced gastric cancer. a 57-year-old male underwent total gastrectomy due to advanced gastric cancer. three years later, a painless hard palpable mass in the left inguinal area developed and th...

background and objective: oral cancer accounts for less than 3% of all cancers. despite recent improvement in diagnostic and treatment methods, the overall survival of the disease is unfavorable. several studies have been performed to assess factors influencing lymph node metastasis and prognosis. the aim of this study was to evaluate some clinical and pathological factors influencing lymph nod...

Metastasis into a thyroid neoplasm-tumor-to-tumor metastasis-is exceedingly rare. We describe the 28th documented case of a tumor metastatic to a thyroid neoplasm and review the literature on tumor-to-tumor metastasis involving a thyroid neoplasm as recipient. All cases showed a recipient thyroid neoplasm with an abrupt transition to a morphologically distinct neoplasm. Metastasis into primary ...

conclusion ct scan is highly accurate in differentiating malignant pleural mesothelioma and metastatic pleural diseases. pleural thickening and thickening of interlobar fissure lead us to the diagnosis of mpm and massive free pleural effusion is more commonly seen in metastatic pleural malignancy. background malignant pleural mesothelioma (mpm) is a rare malignant neoplasm of the pleura that ty...

pulmonary adenocarcinoma is one of the major types of lung cancers in which metastasis is not uncommon. hereby, we report a case of pulmonary adenocarcinoma with multiple muscular, cutaneous, pancreatic and peritoneal metastases. actually, all these features occurring in one patient makes it an extraordinary case. a rare anatomic variation, double inferior vena cava (ivcs), was another rare man...

papillary thyroid carcinoma (ptc) is one of the most commonly diagnosed types of differentiated carcinoma of the thyroid. it is stated that lung is the most common site of metastasis followed by bone. the incidence of paranasal sinus (pns) metastasis is fairly uncommon in case of thyroid carcinoma. to the best of our knowledge, no case of metastatic ptc to nasal cavity has been reported. in thi...

Distant metastasis of gastrointestinal endocrine neoplasm is resistant to currently available treatments. Because hematogenic metastasis is dominant, anti-angiogenic drugs are expected to be a novel therapy for this neoplasm. In the present study, the therapeutic effect of vascular endothelial growth factor neutralizing antibody (VEGFAb) on liver metastasis of an endocrine neoplasm was investig...

objectives: epithelial-mesenchymal transition (emt) is a fundamental stage in cancer metastasis and the presence of vascular invasion is a strong indication of the spread of the malignant tumor cells. regulation of the emt is a complex process in which several different transcription factors are involved. eomesodermin (eomes) as a member of the t-box gene family is an important component in the...

results of the 53 neck dissection specimens, histopathology showed metastases in 16 cases. the overall accuracy of usgfna, us and palpation was 96%, 68% and 70%, respectively. the specificity of usgfna was superior to palpation and us alone. usgfna had the highest sensitivity, predictive value and accuracy in detecting cervical metastases compared with other performed tests. conclusion in our s...

Uterine leiomyosarcoma (ULC) is an uncommon neoplasm characterized by poor prognosis, it can predispose to distant metastasis, causing various symptomatic presentations. We present a unique case of large heterogeneous mass in the lung cavity arising from ULC, with complete absence pulmonary symptoms and concurrent coronavirus disease 2019 (COVID-19) infection. A high degree clinical suspicion r...