Background Neonatal sepsis is one of the major causes of neonatal morbidity and mortality globally. Its incidence varies from 1 to 4 cases per 1,000 live births in developed countries. The burden of the problem occurs in the developing world while most confirmation is derived from developed countries. This study is aimed to assess the prevalence of neonatal sepsi...

background objective: to evaluate the utility of specific cut-off values for c- reactive protein (crp) and immature-to-total neutrophil ratio (i/t) as screening tests for meningitis in culture negative early onset sepsis (eos). materials and methods retrospective chart review of 97 newborns with culture negative sepsis who had lumbar puncture performed as part of the sepsis evaluation in a leve...

objectives the current study aimed to determine the incidence of neonatal infection (nicus) in south sinai neonatal intensive care units, egypt. methods the study included 1023 neonates admitted to neonatal intensive care units in the south sinai state hospitals from january 2010 to september 2014 and scanned for demographic data and the potential risk factors for neonatal septicemia. results t...

conclusions in the present study, we identified a key gene rps16 and a significant module involved in ribosome biogenesis in eukaryotes that were related to neonatal sepsis, which might be potential biomarkers for early detection and therapy for neonatal sepsis. background the exact interacting factor that response to the infection for neonatal sepsis is still needed to urgently to be disclosed...

Sepsis is the most common cause of neonatal mortality. As per National Neonatal-Perinatal Database (NNPD), 2002-2003, the incidence of neonatal sepsis in India was 30 per 1000 live births. Signs and symptoms of sepsis are nonspecific; therefore empirical antimicrobial therapy is promptly initiated after obtaining appropriate cultures. The early manifestations of neonatal sepsis are vague and il...

Background Neonatal sepsis is a type of neonatal infection and specifically refers to the presence in a newborn baby of a bacterial blood stream infection (BSI) in the setting of fever. This study aimed to evaluate the prevalence, pathogen distribution, antibiotic resistance pattern and the most common clinical features in infants with suspected sepsis admitted to teaching hospitals of Ilam, Ir...

background: introduction: searching for an ideal marker for diagnosing neonatal infection is still an important concern in every country. there are many biomarkers reported for neonatal sepsis. haptoglobin is an acute phase reactants which rise in response to infection and injuries. in this report we discussed the efficacy of serum haptoglobin level in different cut off levels in early onset ne...

background: neonatal infections are one of the major causes of death in iran. since identifying the risk factors, types, site, bacterial causes, and case fatality rate of an infection can be effective in selecting preventive and therapeutic methods, and appropriate supportive measures, this study aimed to investigate the aforementioned factors in the neonatal intensive care unit (nicu) of ghaem...

Background & aim: Sepsis is a major cause of neonatal mortality in the developing countries. The prevention and management of this infection require informed workforce and availability of necessary resources and equipment. Regarding this, the present study was conducted to investigate healthcare workers’ neonatal sepsis knowledge; prevention and management strategies in use for the control of t...

Background: Introduction: Searching for an ideal marker for diagnosing neonatal infection is still an important concern in every country. There are many biomarkers reported for neonatal sepsis. Haptoglobin is an acute phase reactants which rise in response to infection and injuries. In this report we discussed the efficacy of serum haptoglobin level in different cut off levels in early onset ne...