Background: Neonatal hyperbilirubinemia occurs in about 60% of newborns. If not managed properly, it can progress to severe neonatal hyperbilirubinemia (SNNJ) leading to death or permanent disability. Aim: To assess nurse's knowledge and practice about neonate with hyperbilirubinemia. Subjects: 41 nurses working in nine districts hospital in Minia governorate each district one hospital and from...

BACKGROUND Hyperbilirubinemia is a common disorder during neonatal period in Taiwan. Gene variants may play an important role in the development of neonatal hyperbilirubinemia. The current study investigated the association between neonatal hyperbilirubinemia and common gene variants involving the production and metabolism of bilirubin. METHODS This prospective study enrolled 444 healthy infa...

BACKGROUND The results of studies on association between the polymorphisms in the coding region and the promoter of uridine diphosphateglucuronosyl transferase 1A1 (UGT1A1) and neonatal hyperbilirubinemia are controversial. This study aimed to determine whether the UGT1A1 gene polymorphisms of Gly71Arg and TATA promoter were significant risk factors associated with neonatal hyperbilirubinemia. ...

background: hyperbilirubinemia is considered one of the most prevalent problems in newborns. phototherapy, exchange transfusion, and herbal medicine are common therapeutic approaches for preventing any neurologic damage in infants with neonatal jaundice. however, herbal medicine is less commonly used. aim: this study aimed to investigate the effect of bilineaster drop on neonatal hyperbilirubin...

Care of the high-risk neonate usually refers to the low-birth-weight infant or the sick term newborn. Whereas hyperbilirubinemia is certainly a matter of concern in these infants, the decisions that must be made regarding jaundice in the high-risk neonate are, in general, less complex than those that must be made for the healthy full-term infant. For the term and near-term infant, shorter hospi...

Unconjugated hyperbilirubinemia is a common condition in the first week of postnatal life. Low levels of bilirubin exert antioxidant effects, but some neonates may develop very high levels of unconjugated bilirubin (UCB), with an increase of the unbound free fraction (Bf), able to diffuse through the blood brain barrier. Amount and duration of hyperbilirubinemia and the neurodevelopmental age (...

thrombocytopenia has been reported as a complication of phototherapy. in this study the effect of conventional phototherapy on platelet count was studied in 101 newborns with indirect hyperbilirubinemia, out of whom 50 patients (49.5%) had decreased levels of platelets; 20 (19.8%) of the latter had a platelet count of below 100000/mm3. decreased platelet count was maximum during the first 24 ho...

introduction: neonatal hyperbilirubinemia is one of the most important factors affecting the auditory system and can cause sensorineural hearing loss. this study investigated the relationship between behavioral hearing thresholds in children with a history of jaundice and the maximum level of bilirubin concentration in the blood.   materials and methods: this study was performed on 18 children ...

After completing this article, readers should be able to: 1. List the risk factors for severe hyperbilirubinemia. 2. Distinguish between physiologic jaundice and pathologic jaundice of the newborn. 3. Recognize the clinical manifestations of acute bilirubin encephalopathy and the permanent clinical sequelae of kernicterus.4. Describe the evaluation of hyperbilirubinemia from birth through 3 mon...

Hyperbilirubinemia is a frequent condition affecting newborns during the first two weeks of life and when it lasts more than 14 days it is defined as prolonged jaundice. This condition requires differential diagnosis between the usually benign unconjugated hyperbilirubinemia and the pathological conjugated hyperbilirubinemia, that is mainly due to neonatal cholestasis. It is important that the ...