Twenty-one cases of presumptive deletion of the short arm of a No. 18 chromosome were recently reviewed by Reinwein et al. (1968) together with a new case from their own material. Five additional reports describing 6 cases have since been published (Grouchy, Rossier, and Joab, 1967; Gilgenkrantz, Marchal, and Neimann, 1968; Gorlin, Yunis, and Anderson, 1968; McDermott et al., 1968; Jacobsen and...

Asphyxiating thoracic dystrophy of the newborn is a rare skeletal abnormality. Though the disease is generalized in distribution, the cartilaginous thoracic cage bears the brunt, with the results that the chest is narrow and immobile. The outcome is usually fatal early in the neonatal period. Less frequently the patients survive with severely impaired respiratory function only to succumb to rep...

Asphyxiating thoracic dystrophy of the newborn is a rare skeletal abnormality. Though the disease is generalized in distribution, the cartilaginous thoracic cage bears the brunt, with the results that the chest is narrow and immobile. The outcome is usually fatal early in the neonatal period. Less frequently the patients survive with severely impaired respiratory function only to succumb to rep...

1. Rapp SR, Feldman SR, Exum ML, Fleischer AB Jr, Reboussin DM. Psoriasis causes as much disability as other major medical diseases. J Am Acad Dermatol 1999;41:401-7. 2. Reed WB, Becker SW, Rhode, Heiskell CL. Psoriasis and arthritis: A clinicopathological study. Arch Dermatol 1961;83:541-8. 3. Gelfand JM, Neimann AL, Shin DB, Wang X, Margolis DJ, Troxel AB. Risk of myocardial infarction in pat...

RENDEL and STORMONT (1964) found that in sheep sera subjected to starch-gel electrophoresis the zone of phosphatase activity which they designated B is highly correlated with the presence of soluble blood-group substance 0 in adult females. Since the presence of 0 substance is recessive to the presence of R substance ( STORMONT 1951 ; RENDEL, NEIMANN-SBRENSEN and IRWIN 1954), they inferred that...

BACKGROUND miRNAs are single-stranded, small RNA molecules with a length of 18-25 nucleotides. They bind to the 3' untranslated regions of mRNA transcripts to reduce the translation of these transcripts or to cause their degradation. The roles of these molecules differ in biological processes, such as cell differentiation, proliferation, apoptosis and tumor genesis. miRNA-33 is encoded by the g...

Sir, The review by Phillips et al. is an insight into the reasoning of the scientific advisors of the animal drug industry. We hope that the industry discounts this bad advice. It would be alarming if preventive action to control resistant human pathogens in the food supply should be taken only when sufficient numbers of humans had been harmed, to enable undisputable epidemiological proof of a ...

L is a neurotoxin that has been shown to adversely affect cognitive functioning and development in children.1 Infants and children are more vulnerable to lead exposure because of the more rapid airway and gastro-intestinal absorption, hand-to-mouth activities, and increased susceptibility of the developing brain to the neurotoxic effects of lead.1 Moreover, children with developmental delay are...